Multi-drug-resistant tuberculosis classification: Difference between revisions
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Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis, | Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis, | ||
The strains are classified as follows. <ref name=WHO>{{cite web | title =Drug resistance Classification| url =http://apps.who.int/iris/bitstream/10665/79199/1/9789241505345_eng.pdf }}</ref> | The strains are classified as follows. <ref name=WHO>{{cite web | title =Drug resistance Classification| url =http://apps.who.int/iris/bitstream/10665/79199/1/9789241505345_eng.pdf }}</ref> | ||
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! style="background: #4479BA; width: 250px;" | {{fontcolor|#FFF|Classification}} | |||
! style="background: #4479BA; width: 350px;" | {{fontcolor|#FFF|Description}} | |||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Monoresistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to any one of the first line anti tubercular drugs | |||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Polydrug resistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to more than one first line anti tubercular drugs. (Other than both rifampicin and isoniazid) | |||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Multidrug resistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Strain resistant to both rifampicin and isoniazid | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Extensive drug resistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" |In addition to the multi drug resistance, strain is resistant to any fluroquinolone and to atleast one of the three second line anti injectable drugs like amikacin, capreomycin and kanamycin. | |||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Rifampicin resistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Using genotypic or phenotypic method, strain has been detected to have resistance to rifampicin with or without resistance to other anti TB drugs. It can include monoresistance, multi drug resistance, poly drug resistance or extensive drug resistance. | |||
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Revision as of 15:54, 26 September 2014
Multi-drug-resistant tuberculosis Microchapters |
Differentiating Multi-drug-resistant tuberculosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Classification
Based on the drug susceptibility testing of cinical isolates confirmed to be Mycobacterium tuberculosis, The strains are classified as follows. [1]
Classification | Description |
---|---|
Monoresistance | Strain resistant to any one of the first line anti tubercular drugs |
Polydrug resistance | Strain resistant to more than one first line anti tubercular drugs. (Other than both rifampicin and isoniazid) |
Multidrug resistance | Strain resistant to both rifampicin and isoniazid |
Extensive drug resistance | In addition to the multi drug resistance, strain is resistant to any fluroquinolone and to atleast one of the three second line anti injectable drugs like amikacin, capreomycin and kanamycin. |
Rifampicin resistance | Using genotypic or phenotypic method, strain has been detected to have resistance to rifampicin with or without resistance to other anti TB drugs. It can include monoresistance, multi drug resistance, poly drug resistance or extensive drug resistance. |