Leukopenia: Difference between revisions

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List of terms related to Leukopenia

	Leukopenia;
ICD-10	D70
ICD-9	288.0
DiseasesDB	32396
MeSH	C15.378.553.546

VisualWikitext

Revision as of 16:56, 11 November 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Leukopenia (or leukocytopenia, or leucopenia or leukopaenia) is a decrease in the number of circulating white blood cells (leukocytes) in the blood. As the principal function of white cells is to combat infection, a decrease in the number of these cells can place patients at increased risk for infection.

In pancytopenia, the other cell types in the blood (red blood cells and platelets) are similarly affected.

Neutropenia is a decrease in the number of circulating neutrophil granulocytes, the most abundant white blood cells. The terms leukopenia and neutropenia may occasionally be used interchangeably, as the neutrophil count is the most important indicator of infection risk. However, neutropenia is more properly considered a subset of leukopenia as a whole.

Low white cell counts are associated with chemotherapy, radiation therapy, leukemia (as malignant cells overwhelm the bone marrow), myelofibrosis and aplastic anemia (failure of white and red cell creation, along with poor platelet production). In addition, many common medications can cause leukopenia.

Other causes of low white blood cell count include: Influenza, systemic lupus erythematosus, typhus, malaria, HIV, tuberculosis, dengue, Rickettsial infections, enlargement of the spleen, folate deficiencies and sepsis. Many other causes exist.

Leukopenia can be identified with a complete blood count.

Acute after certain infections
Agranulocytosis
Alcoholism
Aplastic Anemia
Benign familial neutropenia
Benign neutropenia in black people
Bone marrow damage
Brucellosis
Cachexia
Chickenpox
Chronically in HIV infection
Cyclic neutropenia
Degenerative and inflammatory vasculopathies
Diphtheria
Diuretics
Drug-induced granulocytopenias
Drugs such as Hydroxychloroquine, Metaxalone, Methocarbamol, Mycophenolate, Olanzapine, Oxcarbazepine, Pramipexole
Epstein-Barr Virus
Exanthema subitum
Folic acid deficiency
HIV
Hyperglobulia
Hypersplenism
Hypopituitarism
Hypothyroidism
Idiopathic
Infection
Infectious hepatitis
Infectious mononucleosis
Influenza
Iron deficiency anemia
Kala-Azar
Kostmann Syndrome
Leukemia (acute)
Lipid storage disease
Malaria
Malignant lymphomas
Myeloproliferative disorders
Ornithosis
Osteomyelosclerosis
Paraproteinemia
Paratyphus
Parvovirus B19
Pernicious anemia
Poliomyelitis
Primary and secondary varicosis
Rickettsial infection
Sjogren's Syndrome
Systemic Lupus Erythematosus
Thyrotoxicosis
Toxoplasmosis
Tuberculosis
Tularemia
Tumor infiltration
Typhoid Fever
Varicella
Vein Compression Syndrome
Vitamin B12 Deficiency
Yellow Fever ^[1] ^[2]

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Hydroxychloroquine, Metaxalone, Methocarbamol, Mycophenolate, Olanzapine, Oxcarbazepine, Pramipexole
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

List the causes of the disease in alphabetical order. You may need to list across the page, as seen here

Disease A

Disease B

Disease C

Contraindicated medications

Leukopenia is considered an absolute contraindication to the use of the following medications:

Methotrexate

References

↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

External links

de:Leukopenie it:Leucopenia nl:Leukopenie sk:Leukopénia sv:Leukopeni

Template:WH Template:WS Template:Jb1

[1] Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016

[2] Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

[1]

[2]

@@ Line 90: / Line 90: @@
 * [[Vitamin B12 Deficiency]]
 * [[Yellow Fever]] <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>
+===Causes by Organ System===
+{|style="width:80%; height:100px" border="1"
+|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
+|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
+|-
+|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Dental'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Dermatologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Drug Side Effect'''
+|bgcolor="Beige"| [[Hydroxychloroquine]], [[Metaxalone]], [[Methocarbamol]], [[Mycophenolate]], [[Olanzapine]], [[Oxcarbazepine]], [[Pramipexole]]
+|-
+|-bgcolor="LightSteelBlue"
+| '''Ear Nose Throat'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Endocrine'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Environmental'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Gastroenterologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Genetic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Hematologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Iatrogenic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Infectious Disease'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Musculoskeletal/Orthopedic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Neurologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Nutritional/Metabolic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Obstetric/Gynecologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Oncologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Ophthalmologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Overdose/Toxicity'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Psychiatric'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Pulmonary'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Renal/Electrolyte'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Rheumatology/Immunology/Allergy'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Sexual'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Trauma'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Urologic'''
+|bgcolor="Beige"| No underlying causes
+|-
+|-bgcolor="LightSteelBlue"
+| '''Miscellaneous'''
+|bgcolor="Beige"| No underlying causes
+|-
+|}
+===Causes in Alphabetical Order===
+: List the causes of the disease in alphabetical order. You may need to list across the page, as seen [[Jaundice causes#Causes in Alphabetical Order|here]]
+{{col-begin|width=80%}}
+{{col-break|width=33%}}
+* Disease A
+{{col-break|width=33%}}
+* Disease B
+{{col-break|width=33%}}
+* Disease C
+{{col-end}}