Meningococcemia history and symptoms: Difference between revisions

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*Meningeal infection is similar to other forms of acute purulent [[meningitis]], with sudden onset of [[fever]], [[headache]], and [[stiff neck]], often accompanied by other symptoms, such as [[nausea]], [[vomiting]], [[photophobia]] (eye sensitivity to light), and [[altered mental status]]. Meningococci can be isolated from the blood in up to 75% of persons with [[meningitis]].
*Meningeal infection is similar to other forms of acute purulent [[meningitis]], with sudden onset of [[fever]], [[headache]], and [[stiff neck]], often accompanied by other symptoms, such as [[nausea]], [[vomiting]], [[photophobia]] (eye sensitivity to light), and [[altered mental status]]. Meningococci can be isolated from the blood in up to 75% of persons with [[meningitis]].
*Meningococcal [[sepsis]] (bloodstream [[infection]] or meningococcemia) occurs without [[meningitis]] in 5% to 20% of invasive meningococcal [[infections]]. This condition is characterized by abrupt onset of [[fever]] and a petechial or purpuric [[rash]], often associated with [[hypotension]], [[shock]], [[acute adrenal hemorrhage]], and [[multiorgan failure]].
*Meningococcal [[sepsis]] (bloodstream [[infection]] or meningococcemia) occurs without [[meningitis]] in 5% to 20% of invasive meningococcal [[infections]]. This condition is characterized by abrupt onset of [[fever]] and a petechial or purpuric [[rash]], often associated with [[hypotension]], [[shock]], [[acute adrenal hemorrhage]], and [[multiorgan failure]].
*Less common presentations of meningococcal disease include [[pneumonia]] (5% to 15% of cases), [[arthritis]] (2%), [[otitis media]] (1%), and [[epiglottitis]] (less than 1%).<ref name=CDC>{{cite web | title = The Centers for Disease Control and Prevention(CDC)| url =http://www.cdc.gov/vaccines/pubs/pinkbook/mening.html}}</ref>
*Less common presentations of meningococcal disease include [[pneumonia]] (5% to 15% of cases), [[arthritis]] (2%), [[otitis media]] (1%), and [[epiglottitis]] (less than 1%).<ref name=CDC>{{cite web | title = The Centers for Disease Control and Prevention(CDC)| url=http://www.cdc.gov/meningococcal/about/diagnosis-treatment.html}}</ref>


[[File:Clinical manifestations.png|thumb|center|500px| <SMALL><SMALL> ''[(http://www.cdc.gov/meningococcal/)]''<ref name="CDC">{{Cite web | title =The Centers for Disease Control and Prevention(CDC) | url = http://www.cdc.gov/meningococcal/}}</ref></SMALL></SMALL>]]
[[File:Clinical manifestations.png|thumb|center|500px| <SMALL><SMALL> ''[(http://www.cdc.gov/meningococcal/)]''<ref name="CDC">{{Cite web | title =The Centers for Disease Control and Prevention(CDC) | url = http://www.cdc.gov/meningococcal/}}</ref></SMALL></SMALL>]]

Revision as of 14:27, 21 November 2014

Meningococcemia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Ammu Susheela, M.D. [3]

Overview

Every child with purpuric rash and high fever should be treated as meningococcemia until proven otherwise. The history suggest patient with high fever, rash, headache, myalgia and stiff neck.

History and Symptoms

[(http://commons.wikimedia.org/wiki/File:Symptoms_of_Meningitis.svg)][1]

The following are some of the symptoms found in meningococcus infection. Not all of these symptoms will appear, and not necessarily in this order. Every child with purpuric rash and high fever should be treated as meningococcemia - until proven otherwise.

  • Headache, confusion, and stiff neck occurred as symptoms in less than half of 53 patient in one series by Carpenter and Petersdorf.
  • High fever
  • Mental status changes
  • Nausea and vomiting
  • Patient may complain of significant myalgias.
  • Rash, pinpoint red spots (petechiae)
  • Sensitivity to light (photophobia)
  • Severe headache
  • Severe malaise
  • Stiff neck

HUSSEIN AND SHAFRAN CANADIAN REVIEW OF BACTERIAL MENINGITIS

Fever >= 37.7 degrees Celsius 97%
Nucal Rigidity 87%
Headache 66%
Denied Headache 16%
Nausea/Vomiting 55%
Confusion 56%
Decreased Consciousness 51%
Focal Neurologic Deficits 23%
Seizure 29%
[(http://www.cdc.gov/meningococcal/)][1]

References

  1. 1.0 1.1 1.2 "wikicommons".

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