Loratadine: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{DrugProjectFormSinglePage | {{DrugProjectFormSinglePage | ||
|authorTag={{AP}} | |authorTag={{AP}} | ||
|genericName=Loratadine | |||
|aOrAn=an | |||
|drugClass=antihistamine | |||
|indicationType=treatment | |||
|indication=[[runny nose]], [[sneezing]], itchy, watery eyes, itching of the nose or throat. | |||
|adverseReactions=[[Xerostomia]], [[headache]], [[somnolence]] and [[fatigue]]. | |||
|blackBoxWarningTitle=<b><span style="color:#FF0000;">TITLE</span></b> | |blackBoxWarningTitle=<b><span style="color:#FF0000;">TITLE</span></b> | ||
|blackBoxWarningBody=<i><span style="color:#FF0000;">Condition Name:</span></i> (Content) | |blackBoxWarningBody=<i><span style="color:#FF0000;">Condition Name:</span></i> (Content) | ||
|offLabelAdultGuideSupport= | |fdaLIADAdult=====Seasonal allergic rhinitis==== | ||
*Dose: 10 mg PO daily | |||
====Idiopathic urticaria==== | |||
*Dose: 10 mg PO daily | |||
|offLabelAdultGuideSupport=*[[Asthma]]: 10-20 mg PO daily up to 8 weeks | |||
*[[Eosinophilic nonallergic rhinitis]] | |||
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Loratadine in adult patients. | |offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Loratadine in adult patients. | ||
|fdaLIADPed=*5 mg PO daily | |||
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Loratadine in pediatric patients. | |offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of Loratadine in pediatric patients. | ||
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Loratadine in pediatric patients. | |offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of Loratadine in pediatric patients. | ||
Revision as of 17:17, 15 December 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alberto Plate [2]
Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
Overview
Loratadine is an antihistamine that is FDA approved for the treatment of runny nose, sneezing, itchy, watery eyes, itching of the nose or throat.. Common adverse reactions include Xerostomia, headache, somnolence and fatigue..
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
Seasonal allergic rhinitis
- Dose: 10 mg PO daily
Idiopathic urticaria
- Dose: 10 mg PO daily
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
- Asthma: 10-20 mg PO daily up to 8 weeks
- Eosinophilic nonallergic rhinitis
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Loratadine in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
- 5 mg PO daily
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Loratadine in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Loratadine in pediatric patients.
Contraindications
There is limited information regarding Loratadine Contraindications in the drug label.
Warnings
There is limited information regarding Loratadine Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Loratadine Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Loratadine Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Loratadine Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Loratadine in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Loratadine in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Loratadine during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Loratadine in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Loratadine in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Loratadine in geriatric settings.
Gender
There is no FDA guidance on the use of Loratadine with respect to specific gender populations.
Race
There is no FDA guidance on the use of Loratadine with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Loratadine in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Loratadine in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Loratadine in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Loratadine in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Loratadine Administration in the drug label.
Monitoring
There is limited information regarding Loratadine Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Loratadine and IV administrations.
Overdosage
There is limited information regarding Loratadine overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Loratadine Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Loratadine Mechanism of Action in the drug label.
Structure
There is limited information regarding Loratadine Structure in the drug label.
Pharmacodynamics
There is limited information regarding Loratadine Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Loratadine Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Loratadine Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Loratadine Clinical Studies in the drug label.
How Supplied
There is limited information regarding Loratadine How Supplied in the drug label.
Storage
There is limited information regarding Loratadine Storage in the drug label.
Images
Drug Images
{{#ask: Page Name::Loratadine |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}
Package and Label Display Panel
{{#ask: Label Page::Loratadine |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
There is limited information regarding Loratadine Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Loratadine interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Loratadine Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Loratadine Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
Synonyms / Brand Names:
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]
Dosing and Administration
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Loratadine
Return to top
Publication Resources
Most Recent Articles on Loratadine
Review Articles on Loratadine
Articles on Loratadine in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Loratadine
Return to top
Trial Resources
Ongoing Trials with Loratadine at Clinical Trials.gov
Trial Results with Loratadine
Return to top
Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Loratadine
Cochrane Collaboration on Loratadine
Cost Effectiveness of Loratadine
Return to top
Media Resources
Powerpoint Slides on Loratadine
Images of Loratadine
Podcasts & MP3s on Loratadine
Videos on Loratadine
Return to top
Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Loratadine
Discussion Groups on Loratadine
Patient Handouts on Loratadine
Blogs on Loratadine
Loratadine in the News
Loratadine in the Marketplace
Return to top
International Resources
Loratadine en Español
Return to top
Adapted from the FDA Package Insert.