Pneumonia historical perspective: Difference between revisions
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'''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:charlesmichaelgibson@gmail.com] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com] | '''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:charlesmichaelgibson@gmail.com] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com] | ||
==Overview== | ==Overview== | ||
==Historical Perspective== | ==Historical Perspective== | ||
Revision as of 15:04, 29 December 2014
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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]
Overview
Historical Perspective
The symptoms of pneumonia were initially described by Hippocrates in (c. 460 BC–380 BC):
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Peripneumonia, and pleuritic affections, are to be thus observed: If the fever be acute, and if there be pains on either side, or in both, and if expiration be if cough be present, and the sputa expectorated be of a blond or livid color, or likewise thin, frothy, and florid, or having any other character different from the common. [...] When pneumonia is at its height, the case is beyond remedy if he is not purged, and it is bad if he has dyspnoea, and urine that is thin and acrid, and if sweats come out about the neck and head, for such sweats are bad, as proceeding from the suffocation, rales, and the violence of the disease which is obtaining the upper hand. |
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However, Hippocrates himself referred to pneumonia as a disease "named by the ancients." He also reported the results of surgical drainage of empyemas. Maimonides (1138–1204 AD) also described the symptoms of pneumonia in his writings: "The basic symptoms which occur in pneumonia and which are never lacking are as follows: acute fever, sticking pleuritic pain in the side, short rapid breaths, serrated pulse and cough."[1] This clinical description is quite similar to those found in modern textbooks, and it reflected the extent of medical knowledge through the Middle Ages into the 19th century.
Bacteria was first seen in the airways of individuals who died from pneumonia by Edwin Klebs in 1875.[2] Initial work identifying the two common bacterial causes Streptococcus pneumoniae and Klebsiella pneumoniae was performed by Carl Friedländer[3] and Albert Fränkel (1848-1916)[4] in 1882 and 1884, respectively. Friedländer's initial work introduced the Gram stain, a fundamental laboratory test still used to identify and categorize bacteria. Christian Gram's paper describing the procedure in 1884 helped differentiate the two different bacteria and showed that pneumonia could be caused by more than one microorganism.[5]
Early Classification Schemes
Pathologists originally classified pneumonias by the anatomic changes that were found in the lungs either by direct inspection at autopsy or by its appearance under a microscope. . A lobar pneumonia was described as an infection that only involves a single lobe, or section, of a lung. Multilobar pneumonia involved more than one lobe, and it often causes a more severe illness. Interstitial pneumonia involved the areas in between the alveoli. As more became known about the microorganisms causing pneumonia, a microbiologic classification arose, and with the advent of x-rays, a radiological classification was created as well.The discovery of x-rays made it possible to determine the anatomic type of pneumonia without direct examination of the lungs at autopsy. Early investigators distinguished between typical lobar pneumonia and atypical or viral pneumonia using the location, distribution, and the appearance of the opacities they saw on chest x-rays. Certain x-ray findings can be used to help predict the course of illness, although it is not possible to clearly determine the microbiologic cause of a pneumonia with x-rays alone. Another important system of classification is the combined clinical classification, which combines factors such as age, risk factors for certain microorganisms, the presence of underlying lung disease and underlying systemic disease, and whether the person has recently been hospitalized.
References
- ↑ Maimonides, Fusul Musa ("Pirkei Moshe").
- ↑ Klebs E. Beiträge zur Kenntniss der pathogenen Schistomyceten. VII Die Monadinen. Arch. exptl. Pathol. Parmakol. 1875 Dec 10;4(5/6):40–488.
- ↑ Friedländer C. Über die Schizomyceten bei der acuten fibrösen Pneumonie. Virchow's Arch pathol. Anat. u. Physiol. 1882 Feb 4;87(2):319–324.
- ↑ Fraenkel A. Über die genuine Pneumonie, Verhandlungen des Congress für innere Medicin. Dritter Congress. 1884 April 21;3:17–31.
- ↑ Gram C. Über die isolierte Färbung der Schizomyceten in Schnitt- und Trocken-präparaten. Fortschr. Med. 1884 March 15;2(6):185–189.