Aluminium chloride: Difference between revisions

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{{DrugProjectFormSinglePage
{{DrugProjectFormSinglePage
|authorTag=<!--Overview-->
|authorTag={{Ammu}}
|genericName=Aluminium chloride
|aOrAn=a
|aOrAn=a
|hasBlackBoxWarning=Yes
|drugClass=chemical
|indicationType=treatment
|indication=indicated for the control of minor hemorrhage during dental restorative procedures
|adverseReactions=<!--Black Box Warning-->
|adverseReactions=<!--Black Box Warning-->
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
Line 12: Line 15:


<!--FDA-Labeled Indications and Dosage (Adult)-->
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult======Condition1=====
|fdaLIADAdult=* Indicated for the control of minor hemorrhage during dental restorative procedures.
 
* Dispense a small amount of Hemoban into a clean dappen dish or disposable cup.
* Dosing Information
* For hemorrhage control prior to making a restorative impression, soak a suitable length of retraction cord in Hemoban, then using a cord-packing instrument, place the retraction cord into the gingival sulcus. Hemoban is compatible with all impression techniques – though it is recommended that critical areas be gently rinsed with water prior to application of addition-type (VPS) impression materials to preclude inhibition of the setting reaction of the impression material.
 
* For minor hemorrhage control in situations other than making restorative impressions, soak a cotton pellet in Hemoban and apply for several seconds to the area, then rinse gently with water.
:* Dosage
|offLabelAdultGuideSupport=
 
=====Condition2=====
 
* Dosing Information
 
:* Dosage
 
=====Condition3=====
 
* Dosing Information
 
:* Dosage
 
=====Condition4=====
 
* Dosing Information
 
:* Dosage
 
<!--Off-Label Use and Dosage (Adult)-->
 
<!--Guideline-Supported Use (Adult)-->
|offLabelAdultGuideSupport======Condition1=====
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.


<!--Non–Guideline-Supported Use (Adult)-->
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport======Condition1=====
|offLabelAdultNoGuideSupport=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.


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<!--FDA-Labeled Indications and Dosage (Pediatric)-->
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed======Condition1=====
|fdaLIADPed=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.


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<!--Guideline-Supported Use (Pediatric)-->
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
|offLabelPedGuideSupport=
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


<!--Non–Guideline-Supported Use (Pediatric)-->
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
|offLabelPedNoGuideSupport=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


<!--Contraindications-->
<!--Contraindications-->
|contraindications=* Condition1
|contraindications=* This product should not be used with individuals with known sensitivities to aluminum chloride.
 
|warnings=* Do not swallow. Keep out of reach of children. For professional dental use only.
<!--Warnings-->
|warnings=* Description
 
====Precautions====
 
* Description
 
<!--Adverse Reactions-->
 
<!--Clinical Trials Experience-->
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.


=====Body as a Whole=====


=====Cardiovascular=====
=====Digestive=====
=====Endocrine=====
=====Hematologic and Lymphatic=====
=====Metabolic and Nutritional=====
=====Musculoskeletal=====
=====Neurologic=====
=====Respiratory=====
=====Skin and Hypersensitivy Reactions=====
=====Special Senses=====
=====Urogenital=====
=====Miscellaneous=====
<!--Postmarketing Experience-->
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.


=====Body as a Whole=====
=====Cardiovascular=====
=====Digestive=====
=====Endocrine=====


=====Hematologic and Lymphatic=====
=====Metabolic and Nutritional=====
=====Musculoskeletal=====
=====Neurologic=====
=====Respiratory=====
=====Skin and Hypersensitivy Reactions=====
=====Special Senses=====
=====Urogenital=====
=====Miscellaneous=====
<!--Drug Interactions-->
|drugInteractions=* Drug
:* Description
<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
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<!--Administration and Monitoring-->
<!--Administration and Monitoring-->
|administration=* Oral
|administration=* Topical
 
* Intravenous
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
* Description


<!--IV Compatibility-->
<!--IV Compatibility-->
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<!--Overdosage-->
<!--Overdosage-->
|overdose====Acute Overdose===
|overdose=
 
====Signs and Symptoms====
 
* Description
 
====Management====
 
* Description
 
===Chronic Overdose===
 
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.


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<!--Drug box 2-->
<!--Drug box 2-->
|drugBox=<!--Mechanism of Action-->
|drugBox={{chembox2
|mechAction=*
| Watchedfields = changed
| verifiedrevid = 477245740
| Name =
| ImageFile1 = Aluminium-trichloride-hexahydrate-white-and-yellow.jpg
<!-- | ImageSize = 150px -->
| ImageName1 = Aluminium chloride
| ImageFile2 =
| ImageName2 = Aluminium(III) Chloride
| ImageFile3 = Aluminium-trichloride-dimer-3D-balls.png
<!-- | ImageSize1 = 150px  -->
| ImageName3 = Aluminium trichloride dimer
| IUPACName = aluminium chloride
| OtherNames = aluminium(III) chloride
| Section1 = {{Chembox Identifiers
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = LIF1N9568Y
| InChI = 1/Al.3ClH/h;3*1H/q+3;;;/p-3
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 30114
| SMILES = Cl[Al](Cl)Cl
| InChIKey = VSCWAEJMTAWNJL-DFZHHIFOAR
| SMILES1 = [Al](Cl)(Cl)Cl
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/Al.3ClH/h;3*1H/q+3;;;/p-3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VSCWAEJMTAWNJL-UHFFFAOYSA-K
| CASNo = 7446-70-0
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo_Comment = (anhydrous)
| CASNo1 = 10124-27-3
| CASNo1_Comment = (hydrate)
| CASNo2 = 7784-13-6
| CASNo2_Comment = (hexahydrate)
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID=22445
| PubChem = 24012
| RTECS = BD0530000
| ATCCode_prefix = D10
| ATCCode_suffix = AX01
}}
| Section2 = {{Chembox Properties
| Formula = AlCl<sub>3</sub>
| MolarMass = 133.34 g/mol (anhydrous)<br />241.43 g/mol (hexahydrate)
| Appearance = white or pale yellow solid,<br />[[hygroscopic]]
| Density = 2.48 g/cm<sup>3</sup> (anhydrous)<br> 1.3 g/cm<sup>3</sup> (hexahydrate)
| Solubility = 43.9 g/100 ml (0 °C)<br />44.9 g/100 ml (10 °C)<br />45.8 g/100 ml (20 °C)<br />46.6 g/100 ml (30 °C)<br />47.3 g/100 ml (40 °C)<br />48.1 g/100 ml (60 °C)<br />48.6 g/100 ml (80 °C)<br />49 g/100 ml (100 °C)
| SolubleOther = soluble in hydrogen chloride, ethanol, chloroform, carbon tetrachloride <br> slightly soluble in benzene
| MeltingPtC = 192.4
| Melting_notes = <br> (anhydrous)<br> {{convert|100|C|F K}}<br> (hexahydrate)<br> {{convert|180|C|F K}}<br> (sublimes)
| BoilingPtC = 120
| Boiling_notes = (hexahydrate)
| pKa =
| Viscosity = 0.35 cP (197 °C)<br> 0.26 cP (237 °C)<ref name=chemister>http://chemister.ru/Database/properties-en.php?dbid=1&id=353</ref>
| VaporPressure = 133.3 Pa (99 °C)<br> 13.3 kPa (151 °C)<ref name=chemister />
}}
| Section3 = {{Chembox Structure
| MolShape = Trigonal planar<br />([[monomer]]ic vapour)
| Coordination = Octahedral (solid)<br />Tetrahedral (liquid)
| CrystalStruct = [[Monoclinic]], [[Pearson symbol|mS16]]
| SpaceGroup = C12/m1, No. 12
}}
| Section4 = {{Chembox Thermochemistry
|  DeltaHf = −704.2 kJ/mol<ref name=chemister /><ref name = zumdahl>{{cite book| author = Zumdahl, Steven S.|title =Chemical Principles 6th Ed.| publisher = Houghton Mifflin Company| year = 2009| isbn = 0-618-94690-X}}</ref>
|  Entropy = 111 J/mol·K<ref name = zumdahl/>
|  DeltaGf = -628.6 kJ/mol<ref name=chemister />
|  HeatCapacity = 91 J/mol·K<ref name=chemister />
}}
| Section7 = {{Chembox Hazards
| GHSPictograms = {{GHS05}}<ref name="sigma">{{Sigma-Aldrich|id=563919|name=Aluminum chloride|accessdate=2014-05-05}}</ref>
| GHSSignalWord = Danger
| HPhrases = {{H-phrases|314}}<ref name="sigma" />
| PPhrases = {{P-phrases|280|310|305+351+338}}<ref name="sigma" />
| NFPA-H = 3
| NFPA-F = 0
| NFPA-R = 2
| EUClass = {{Hazchem C}}
| RPhrases = {{R34}}
| SPhrases = {{S1/2}}, {{S7/8}}, {{S28}}, {{S45}}
| LD50 = ''anhydrous:'' <br> 380 mg/kg, rat (oral) <hr> ''hexahydrate:'' <br> 3311 mg/kg, rat (oral)
}}
| Section8 = {{Chembox Related
| OtherAnions = [[Aluminium fluoride]]<br />[[Aluminium bromide]]<br />[[Aluminium iodide]]
| OtherCations = [[Boron trichloride]]<br />[[Gallium trichloride]]<br />[[Indium(III) chloride]]<br />[[Magnesium chloride]]
| Function = [[Lewis acid]]s
| OtherFunctn = [[Iron(III) chloride]]<br />[[Boron trifluoride]]
}}
}}
|mechAction=


<!--Structure-->
<!--Structure-->
|structure=*  
|structure=* Hemoban is formulated to control minor hemorrhage during dental restorative procedures. Hemoban may be used on a cotton pellet or more commonly with retraction cord. Hemoban contains 25% aluminum chloride.
 
: [[File:{{PAGENAME}}01.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
 
<!--Pharmacodynamics-->
<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
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<!--Brand Names-->
<!--Brand Names-->
|brandNames=* ®<ref>{{Cite web | title = | url = }}</ref>
|brandNames=*HEMOBAN ®<ref>{{Cite web | title = HEMOBAN- aluminum chloride solution | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7054c4ea-fee2-4627-aff2-e99ceb1080c7 }}</ref>


<!--Look-Alike Drug Names-->
<!--Look-Alike Drug Names-->
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<!--Drug Shortage Status-->
<!--Drug Shortage Status-->
|drugShortage=
|drugShortage=
}}
{{PillImage
|fileName=No image.jpg
}}
}}
{{LabelImage
{{LabelImage
|fileName={{PAGENAME}}11.png
|fileName=Aluminium chloride.jpg
}}
}}
{{LabelImage
{{LabelImage
|fileName={{PAGENAME}}11.png
|fileName=DailyMed - HEMOBAN- aluminum chloride solution  .png
}}
}}
<!--Pill Image-->
<!--Pill Image-->

Revision as of 04:36, 9 January 2015

Aluminium chloride
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Aluminium chloride is a chemical that is FDA approved for the treatment of indicated for the control of minor hemorrhage during dental restorative procedures. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

  • Indicated for the control of minor hemorrhage during dental restorative procedures.
  • Dispense a small amount of Hemoban into a clean dappen dish or disposable cup.
  • For hemorrhage control prior to making a restorative impression, soak a suitable length of retraction cord in Hemoban, then using a cord-packing instrument, place the retraction cord into the gingival sulcus. Hemoban is compatible with all impression techniques – though it is recommended that critical areas be gently rinsed with water prior to application of addition-type (VPS) impression materials to preclude inhibition of the setting reaction of the impression material.
  • For minor hemorrhage control in situations other than making restorative impressions, soak a cotton pellet in Hemoban and apply for several seconds to the area, then rinse gently with water.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Aluminium chloride in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Aluminium chloride in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Aluminium chloride in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Aluminium chloride in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Aluminium chloride in pediatric patients.

Contraindications

  • This product should not be used with individuals with known sensitivities to aluminum chloride.

Warnings

  • Do not swallow. Keep out of reach of children. For professional dental use only.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Aluminium chloride in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Aluminium chloride in the drug label.

Drug Interactions

There is limited information regarding Aluminium chloride Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Aluminium chloride in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Aluminium chloride during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Aluminium chloride with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Aluminium chloride with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Aluminium chloride with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Aluminium chloride with respect to specific gender populations.

Race

There is no FDA guidance on the use of Aluminium chloride with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Aluminium chloride in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Aluminium chloride in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Aluminium chloride in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Aluminium chloride in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Topical

Monitoring

There is limited information regarding Monitoring of Aluminium chloride in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Aluminium chloride in the drug label.

Overdosage

There is limited information regarding Chronic Overdose of Aluminium chloride in the drug label.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox VaporPressureTemplate:Chembox ViscosityTemplate:Chembox StructureTemplate:Chembox ThermochemistryTemplate:Chembox GHSPictogramsTemplate:Chembox GHSSignalWordTemplate:Chembox HPhrasesTemplate:Chembox PPhrasesTemplate:Chembox NFPATemplate:Chembox Lethal amounts (set)Template:Chembox OtherAnionsTemplate:Chembox OtherCationsTemplate:Chembox Supplement
Template:Chembox header2 | Aluminium chloride
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
UNII
Properties
AlCl3
Molar mass 133.34 g/mol (anhydrous)
241.43 g/mol (hexahydrate)
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Aluminium chloride Mechanism of Action in the drug label.

Structure

  • Hemoban is formulated to control minor hemorrhage during dental restorative procedures. Hemoban may be used on a cotton pellet or more commonly with retraction cord. Hemoban contains 25% aluminum chloride.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Aluminium chloride in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Aluminium chloride in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Aluminium chloride in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Aluminium chloride in the drug label.

How Supplied

Storage

There is limited information regarding Aluminium chloride Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Aluminium chloride |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Aluminium chloride |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Aluminium chloride in the drug label.

Precautions with Alcohol

  • Alcohol-Aluminium chloride interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ 1.0 1.1 http://chemister.ru/Database/properties-en.php?dbid=1&id=353
  2. ↑ 2.0 2.1 2.2 Template:Sigma-Aldrich
  3. ↑ "HEMOBAN- aluminum chloride solution".
  4. ↑ "http://www.ismp.org". External link in |title= (help)

{{#subobject: 

 |Label Page=Aluminium chloride
 |Label Name=Aluminium chloride.jpg

}}

{{#subobject: 

 |Label Page=Aluminium chloride
 |Label Name=DailyMed - HEMOBAN- aluminum chloride solution  .png

}}

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