Bone marrow disorders: Difference between revisions

Revision as of 14:47, 16 February 2015

For congenital bone marrow disorders click here.
For acquired bone marrow disorders click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]; Yazan Daaboul, M.D.; Serge Korjian M.D.

Bone marrow suppression: Reduced numbers of cells in bone marrow
- Myelosuppression: Reduced number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunosuppression or lymphosuppression: Reduced number of lymphoid lineage cells (T-cell, B-cell, NK cell)

Bone marrow proliferation: Increased numbers of cells in bone marrow
- Myeloproliferation: Increased number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunoproliferation or lymphoproliferation: Increased number of lymphoid lineage cells (T-cell, B-cell, NK cell)

Shown below is an algorithm depicting the different classes of bone marrow disorders.

Bone Marrow Disorders

Acquired disorders of the bone marrow

Congenital disorders of the bone marrow

Bone marrow suppression

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 * '''Bone marrow proliferation''': Increased numbers of cells in bone marrow
-** '''Myeloproliferation''': Reduced number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
+** '''Myeloproliferation''': Increased number of [[myeloid]] lineage cells ([[RBC]], [[neutrophils]], [[basophils]], [[eosinophils]], [[monocyte]]s, [[platelets]], [[mastocytes]])
-** '''Immunoproliferation or lymphoproliferation''': Reduced number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])
+** '''Immunoproliferation or lymphoproliferation''': Increased number of [[lymphoid]] lineage cells ([[T-cell]], [[B-cell]], [[NK cell]])
 ==Classification==