Bone marrow disorders: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
'''''For congenital bone marrow disorders click [[congenital bone marrow disorders|here]].'''''<br> | '''''For congenital bone marrow disorders, click [[congenital bone marrow disorders|here]].'''''<br> | ||
'''''For acquired bone marrow disorders click [[acquired bone marrow disorders|here]].''''' | '''''For acquired bone marrow disorders, click [[acquired bone marrow disorders|here]].''''' | ||
{{CMG}} | {{CMG}} {{AE}} {{YD}}; {{Rim}}; {{SSK}} | ||
==Overview== | ==Overview== |
Revision as of 23:32, 20 August 2015
For congenital bone marrow disorders, click here.
For acquired bone marrow disorders, click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Rim Halaby, M.D. [2]; Serge Korjian M.D.
Overview
Bone marrow disorders are classified into congenital bone marrow disorders and acquired bone marrow disorders.
Definition of Terms
- Bone marrow suppression: Reduced numbers of cells in bone marrow
- Myelosuppression: Reduced number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunosuppression or lymphosuppression: Reduced number of lymphoid lineage cells (T-cell, B-cell, NK cell)
- Bone marrow proliferation: Increased numbers of cells in bone marrow
- Myeloproliferation: Increased number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunoproliferation or lymphoproliferation: Increased number of lymphoid lineage cells (T-cell, B-cell, NK cell)
Classification
Shown below is an algorithm depicting the different classes of bone marrow disorders.
Bone Marrow Disorders | |||||||||||||||||||||||||||||||||||||||||||||||||||
Myelosuppression | Immunosuppression | Myeloproliferation | Immunoproliferation | Multiple lineages | Single lineage | ||||||||||||||||||||||||||||||||||||||||||||||