Anaplastic large cell lymphoma, ALK positive: Difference between revisions
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==Overview== | ==Overview== | ||
The Anaplastic large cell lymphoma ALK-positive ('''A'''naplastic '''L'''lymphoma '''K'''inase) consist of T-cells with abundant cytoplasm and a pleomorphic nucleus (horseshoe-shaped nucleus). This ALK-positive lymphoma has a translocation in the ALK gene, which will in turn, express the ALK protein<ref name=Swerdlow>{{cite book | last = Swerdlow | first = Steven | title = WHO classification of tumours of haematopoietic and lymphoid tissues | publisher = International Agency for Research on Cancer | location = Lyon, France | year = 2008 | isbn = 9789283224310 }}</ref>. | |||
==Historical Perspective== | ==Historical Perspective== |
Revision as of 19:38, 18 February 2015
Template:DiseaseDisorder infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alberto Plate [2]
Synonyms and keywords:
Overview
The Anaplastic large cell lymphoma ALK-positive (Anaplastic Llymphoma Kinase) consist of T-cells with abundant cytoplasm and a pleomorphic nucleus (horseshoe-shaped nucleus). This ALK-positive lymphoma has a translocation in the ALK gene, which will in turn, express the ALK protein[1].
Historical Perspective
Classification
Pathophysiology
Causes
Differential Diagnosis
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Treatment
References
- ↑ Swerdlow, Steven (2008). WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer. ISBN 9789283224310.