BACOD regimen: Difference between revisions

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Revision as of 16:14, 27 February 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: BACOD; BLEO/CTX/DM/DOX/VCR; Bleomycin/Cyclophosphamide/Dexamethasone/Doxorubicin/Vincristine regimen

Overview

BACOD regimen refers to an immunochemotherapy regimen consisting of bleomycin, doxorubicin, cyclophosphamide ,vincristine ,dexamethasone used to treat relapsed and refractory diffuse large B cell lymphoma .^[1]^[2]

Regimen

B – Bleomycin

A – Doxorubicin (Adriamycin)

C – Cyclophosphamide

O – Vincristine (Oncovin)

D – Dexamethasone

Indications

Relapsed and refractoryDiffuse large B-cell lymphoma ^[3]

References

↑ "NCI Thesaurus".
↑ "R-CHOP - National Cancer Institute".
↑ Gong G, Du J, Dong L, Lei W, Gao X, Fang B; et al. (2014). "[Efficacy of adjusted BACOD regimen on the treatment of relapsed refractory diffuse large B cell lymphoma]". Zhonghua Xue Ye Xue Za Zhi. 35 (4): 295–9. doi:10.3760/cma.j.issn.0253-2727.2014.04.010. PMID 24759015.

[1] "NCI Thesaurus".

[2] "R-CHOP - National Cancer Institute".

[pmid24759015-3] Gong G, Du J, Dong L, Lei W, Gao X, Fang B; et al. (2014). "[Efficacy of adjusted BACOD regimen on the treatment of relapsed refractory diffuse large B cell lymphoma]". Zhonghua Xue Ye Xue Za Zhi. 35 (4): 295–9. doi:10.3760/cma.j.issn.0253-2727.2014.04.010. PMID 24759015.

[1]

[2]

[3]

@@ Line 3: / Line 3: @@
 {{CMG}}; {{AE}} {{AV}}
-{{SK}} BACOD
+{{SK}} BACOD; BLEO/CTX/DM/DOX/VCR; Bleomycin/Cyclophosphamide/Dexamethasone/Doxorubicin/Vincristine regimen
-BLEO/CTX/DM/DOX/VCR
-Bleomycin/Cyclophosphamide/Dexamethasone/Doxorubicin/Vincristine regimen
 ==Overview==
-{{PAGENAME}} refers to an immunochemotherapy regimen consisting of [[rituximab]], [[cyclophosphamide]], [[doxorubicin |hydroxydaunorubicin hydrochloride (doxorubicin hydrochloride)]], [[vincristine|vincristine (Oncovin)]] and [[prednisone]] used to treat both indolent and aggressive forms of [[non-Hodgkin lymphoma]].<ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C63452 }}</ref><ref>{{Cite web | title = R-CHOP - National Cancer Institute | accessdate =  | url = http://www.cancer.gov/cancertopics/druginfo/R-CHOP }}</ref>
+{{PAGENAME}} refers to an immunochemotherapy regimen consisting of [[bleomycin]], [[doxorubicin]], [[cyclophosphamide]] ,[[vincristine]] ,[[dexamethasone]] used to treat relapsed and refractory diffuse large B cell lymphoma .<ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C63452 }}</ref><ref>{{Cite web | title = R-CHOP - National Cancer Institute | accessdate =  | url = http://www.cancer.gov/cancertopics/druginfo/R-CHOP }}</ref>
 ==Regimen==
-[[Rituximab|{{button|R – Rituximab}}]]
+[[Bleomycin|{{button|B – Bleomycin}}]]
+[[Doxorubicin|{{button|A – Doxorubicin (Adriamycin)}}]]
 [[Cyclophosphamide|{{button|C – Cyclophosphamide}}]]
-[[Doxorubicin|{{button|H – Doxorubicin (Hydroxydaunomycin)}}]]
 [[Vincristine|{{button|O – Vincristine (Oncovin)}}]]
-[[Prednisone|{{button|P – Prednisone}}]]
+[[Dexamethasone|{{button|D – Dexamethasone}}]]
 ==Indications==
-* [[Diffuse large B-cell lymphoma|Diffuse large B-cell lymphoma, untreated]]<ref>{{Cite journal | doi = 10.1056/NEJMoa011795 | issn = 1533-4406 | volume = 346 | issue = 4 | pages = 235–242 | last = Coiffier | first = Bertrand | coauthors = Eric Lepage, Josette Briere, Raoul Herbrecht, Hervé Tilly, Reda Bouabdallah, Pierre Morel, Eric Van Den Neste, Gilles Salles, Philippe Gaulard, Felix Reyes, Pierre Lederlin, Christian Gisselbrecht | title = CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma | journal = The New England Journal of Medicine | date = 2002-01-24 | pmid = 11807147 }}</ref>
+* Relapsed and refractory[[Diffuse large B-cell lymphoma]] <ref name="pmid24759015">{{cite journal| author=Gong G, Du J, Dong L, Lei W, Gao X, Fang B et al.| title=[Efficacy of adjusted BACOD regimen on the treatment of relapsed refractory diffuse large B cell lymphoma]. | journal=Zhonghua Xue Ye Xue Za Zhi | year= 2014 | volume= 35 | issue= 4 | pages= 295-9 | pmid=24759015 | doi=10.3760/cma.j.issn.0253-2727.2014.04.010 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24759015  }} </ref>
-* [[Mantle cell lymphoma]]<ref>{{Cite journal | doi = 10.1056/NEJMoa1200920 | issn = 1533-4406 | volume = 367 | issue = 6 | pages = 520–531 | last = Kluin-Nelemans | first = H. C. | coauthors = E. Hoster, O. Hermine, J. Walewski, M. Trneny, C. H. Geisler, S. Stilgenbauer, C. Thieblemont, U. Vehling-Kaiser, J. K. Doorduijn, B. Coiffier, R. Forstpointner, H. Tilly, L. Kanz, P. Feugier, M. Szymczyk, M. Hallek, S. Kremers, G. Lepeu, L. Sanhes, J. M. Zijlstra, R. Bouabdallah, P. J. Lugtenburg, M. Macro, M. Pfreundschuh, V. Procházka, F. Di Raimondo, V. Ribrag, M. Uppenkamp, M. André, W. Klapper, W. Hiddemann, M. Unterhalt, M. H. Dreyling | title = Treatment of older patients with mantle-cell lymphoma | journal = The New England Journal of Medicine | date = 2012-08-09 | pmid = 22873532 }}</ref>
 ==References==