SMILE regimen: Difference between revisions
Created page with "__NOTOC__ {{SI}} {{CMG}}; {{AE}} {{AV}} {{SK}} ==Overview== {{PAGENAME}} refers to a regimen consisting of xxx used to treat xxx. ==Regimen== {{chemo|x|xx}} {{chemo|x|xx}}..." |
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{{SI}} | {{SI}} | ||
{{CMG}}; {{AE}} {{AV}} | {{CMG}}; {{AE}} {{AV}} | ||
==Overview== | ==Overview== | ||
{{PAGENAME}} refers to a regimen consisting of | {{PAGENAME}} refers to a regimen consisting of [[Dexamethasone|Steroid (Dexamethasone)]], [[Methotrexate]], [[Ifosfamide]], [[L-asparaginase]], [[Etoposide]] used to treat [[T-cell lymphoma|NK/T-cell lymphoma]]<ref name="pmid18294294">{{cite journal| author=Yamaguchi M, Suzuki R, Kwong YL, Kim WS, Hasegawa Y, Izutsu K et al.| title=Phase I study of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy for advanced-stage, relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma and leukemia. | journal=Cancer Sci | year= 2008 | volume= 99 | issue= 5 | pages= 1016-20 | pmid=18294294 | doi=10.1111/j.1349-7006.2008.00768.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18294294 }} </ref> | ||
==Regimen== | ==Regimen== | ||
{{chemo| | {{chemo|S|Steroid (Dexamethasone)}} | ||
{{chemo|M|Methotrexate}} | |||
{{chemo|I|Ifosfamide}} | |||
{{chemo| | {{chemo|L|L-asparaginase}} | ||
{{chemo| | {{chemo|E|Etoposide}} | ||
==Indications== | ==Indications== | ||
*[[T-cell lymphoma|NK/T-cell lymphoma]]<ref name="pmid18294294">{{cite journal| author=Yamaguchi M, Suzuki R, Kwong YL, Kim WS, Hasegawa Y, Izutsu K et al.| title=Phase I study of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy for advanced-stage, relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma and leukemia. | journal=Cancer Sci | year= 2008 | volume= 99 | issue= 5 | pages= 1016-20 | pmid=18294294 | doi=10.1111/j.1349-7006.2008.00768.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18294294 }} </ref> | |||
Revision as of 18:24, 30 March 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]
Overview
SMILE regimen refers to a regimen consisting of Steroid (Dexamethasone), Methotrexate, Ifosfamide, L-asparaginase, Etoposide used to treat NK/T-cell lymphoma[1]
Regimen
SSteroid (Dexamethasone)
MMethotrexate
IIfosfamide
LL-asparaginase
EEtoposide
Indications
References
- ↑ 1.0 1.1 Yamaguchi M, Suzuki R, Kwong YL, Kim WS, Hasegawa Y, Izutsu K; et al. (2008). "Phase I study of dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide (SMILE) chemotherapy for advanced-stage, relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma and leukemia". Cancer Sci. 99 (5): 1016–20. doi:10.1111/j.1349-7006.2008.00768.x. PMID 18294294.