Nephrotic syndrome causes: Difference between revisions
Rim Halaby (talk | contribs) /* List of Secondary Causes of Nephrotic Syndrome{{cite journal| author=Eddy AA, Symons JM| title=Nephrotic syndrome in childhood. | journal=Lancet | year= 2003 | volume= 362 | issue= 9384 | pages= 629-39 | pmid=12944064 | doi=10.1016/S0140-6736(03)141... |
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==Causes== | ==Causes== | ||
===Primary Causes=== | ===Primary Causes=== | ||
Primary renal disorders, such as primary glomerulonephritides, may cause primary nephrotic syndrome. Differentiation between different types of glomerular diseases is often made by clinical suspicion and by renal biopsy, which includes light microscopy, immunofluorescence, and ideally electron microscopy. | Primary renal disorders, such as primary [[glomerulonephritides]], may cause primary nephrotic syndrome. Differentiation between different types of glomerular diseases is often made by clinical suspicion and by renal biopsy, which includes [[light microscopy]], [[immunofluorescence]], and ideally [[electron microscopy]]. | ||
===Secondary Causes=== | ===Secondary Causes=== | ||
Secondary causes of renal disorders cause secondary nephrotic syndrome. The most common cause of secondary nephrotic syndrome in adults is diabetes mellitus. | Secondary causes of renal disorders cause secondary nephrotic syndrome. The most common cause of secondary nephrotic syndrome in adults is [[diabetes mellitus]]. Shown below is a table of the causes of nephrotic syndrome by age group. | ||
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|- | |- | ||
| bgcolor="#ececec"|'''< 15 ''' || | | bgcolor="#ececec"|'''< 15 ''' || | ||
*Congenital nephrotic syndrome | *[[Congenital]] nephrotic syndrome | ||
*Minimal change disease | *[[Minimal change disease]] | ||
*Focal segmental glomerulosclerosis | *[[Focal segmental glomerulosclerosis]] | ||
*Membranous nephropathy | *[[Membranous nephropathy]] | ||
|- | |- | ||
| bgcolor="#ececec"|'''15-40''' || | | bgcolor="#ececec"|'''15-40''' || | ||
*Focal segmental glomerulosclerosis | *[[Focal segmental glomerulosclerosis]] | ||
*Lupus nephritis | *[[Lupus nephritis]] | ||
*Minimal change disease | *[[Minimal change disease]] | ||
*Membranous nephropathy | *[[Membranous nephropathy]] | ||
*Diabetic nephropathy | *[[Diabetic nephropathy]] | ||
*Pre-eclampsia | *[[Pre-eclampsia]] | ||
*Late post-infectious glomerulonephritis | *Late [[post-infectious glomerulonephritis]] | ||
*IgA nephropathy | *[[IgA nephropathy]] | ||
|- | |- | ||
| bgcolor="#ececec"|'''> 40 ''' || | | bgcolor="#ececec"|'''> 40 ''' || | ||
*Focal segmental glomerulosclerosis | *[[Focal segmental glomerulosclerosis]] | ||
*Membranous nephropathy | *[[Membranous nephropathy]] | ||
*Diabetic nephropathy | *[[Diabetic nephropathy]] | ||
*Minimal change disease | *[[Minimal change disease]] | ||
*IgA nephropathy | *[[IgA nephropathy]] | ||
*Primary amyloidosis | *[[Primary amyloidosis]] | ||
*Light chain deposition disease | *[[Light chain deposition disease]] | ||
*Benign nephrosclerosis | *[[Benign nephrosclerosis]] | ||
*Late post-infectious glomerulonephritis | *Late [[post-infectious glomerulonephritis]] | ||
|} | |} | ||
Revision as of 02:29, 5 April 2015
Nephrotic Syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian
Overview
Nephrotic syndrome can be either primary or secondary to diseases. Primary renal disorders, such as primary glomerulonephritides, may cause primary nephrotic syndrome. The most common cause of secondary nephrotic syndrome in adults is diabetes mellitus.
Causes
Primary Causes
Primary renal disorders, such as primary glomerulonephritides, may cause primary nephrotic syndrome. Differentiation between different types of glomerular diseases is often made by clinical suspicion and by renal biopsy, which includes light microscopy, immunofluorescence, and ideally electron microscopy.
Secondary Causes
Secondary causes of renal disorders cause secondary nephrotic syndrome. The most common cause of secondary nephrotic syndrome in adults is diabetes mellitus. Shown below is a table of the causes of nephrotic syndrome by age group.
Age (Years) | Cause of Nephrotic Syndrome |
< 15 |
|
15-40 | |
> 40 |
List of Secondary Causes of Nephrotic Syndrome[1]
- Adaptation to nephron reduction
- Amyloidosis
- Bee sting
- Castleman's disease
- Chronic interstitial nephritis
- Dermatomyositis
- Diabetes mellitus
- Endocarditis
- Fabry's disease
- Food allergens
- Gold
- Goodpasture's syndrome
- Graft vs. host disease
- Henoch-Schonlein purpura
- Heroin
- HIV
- Infectious mononeucliosis
- Interferon
- Kimura's disease
- Leukemia
- Lipoatrophy
- Lithium
- Lymphomas
- Malaria
- Mercury
- Mixed connective tissue disease
- Multiple myeloma
- NSAID
- Obesity
- Oligomeganephronia
- Orthostatic proteinuria
- Penicillamine
- Polyarteritis nodosa
- Pre-eclampsia
- Probenecid
- Renal vein thrombosis
- Rheumatoid arthritis
- Sarcoidosis
- Sickle cell anemia
- Sjogren's syndrome
- Sorafenib
- Streptococcal Infection
- Syphillis
- Systemic lupus erythematosus
- Thyroid disease
- Toxoplasmosis
- Vasculitis
- Viral Hepatitis
Drug Induced
References
- ↑ Eddy AA, Symons JM (2003). "Nephrotic syndrome in childhood". Lancet. 362 (9384): 629–39. doi:10.1016/S0140-6736(03)14184-0. PMID 12944064.