Tirilazad: Difference between revisions

	WikiDoc Resources for Tirilazad
Articles
Most recent articles on Tirilazad Most cited articles on Tirilazad Review articles on Tirilazad Articles on Tirilazad in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Tirilazad Images of Tirilazad Photos of Tirilazad Podcasts & MP3s on Tirilazad Videos on Tirilazad
Evidence Based Medicine
Cochrane Collaboration on Tirilazad Bandolier on Tirilazad TRIP on Tirilazad
Clinical Trials
Ongoing Trials on Tirilazad at Clinical Trials.gov Trial results on Tirilazad Clinical Trials on Tirilazad at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Tirilazad NICE Guidance on Tirilazad NHS PRODIGY Guidance FDA on Tirilazad CDC on Tirilazad
Books
Books on Tirilazad
News
Tirilazad in the news Be alerted to news on Tirilazad News trends on Tirilazad
Commentary
Blogs on Tirilazad
Definitions
Definitions of Tirilazad
Patient Resources / Community
Patient resources on Tirilazad Discussion groups on Tirilazad Patient Handouts on Tirilazad Directions to Hospitals Treating Tirilazad Risk calculators and risk factors for Tirilazad
Healthcare Provider Resources
Symptoms of Tirilazad Causes & Risk Factors for Tirilazad Diagnostic studies for Tirilazad Treatment of Tirilazad
Continuing Medical Education (CME)
CME Programs on Tirilazad
International
Tirilazad en Espanol Tirilazad en Francais
Business
Tirilazad in the Marketplace Patents on Tirilazad
Experimental / Informatics
List of terms related to Tirilazad

Tirilazad
Clinical data
Synonyms	(8S,10S,13S,14S,16R,17S)-17-[2-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]acetyl]-10,13,16-trimethyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
ATC code	N07XX01 (WHO) ;
Identifiers
	IUPAC name (16α)-21-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]-16-methylpregna-1,4,9(11)-triene-3,20-dione;
CAS Number	110101-66-1 ;
PubChem CID	104903;
ChemSpider	94673 ;
UNII	YD064E883I;
KEGG	D08606 ;
ChEMBL	ChEMBL1630578 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C38H52N6O2
Molar mass	624.859 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(CN4CCN(c2nc(nc(N1CCCC1)c2)N3CCCC3)CC4)[C@H]6[C@H](C)C[C@H]5[C@H]8C(=C/C[C@@]56C)\[C@]/7(/C=C\C(=O)\C=C\7CC8)C;
	InChI InChI=1S/C38H52N6O2/c1-26-22-31-29-9-8-27-23-28(45)10-12-37(27,2)30(29)11-13-38(31,3)35(26)32(46)25-41-18-20-43(21-19-41)34-24-33(42-14-4-5-15-42)39-36(40-34)44-16-6-7-17-44/h10-12,23-24,26,29,31,35H,4-9,13-22,25H2,1-3H3/t26-,29-,31+,35-,37+,38+/m1/s1 ; Key:RBKASMJPSJDQKY-RBFSKHHSSA-N ;
(what is this?) (verify)

Newer edit →

VisualWikitext

Revision as of 19:30, 6 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tirilazad is a drug proposed to treat acute ischaemic stroke, however results are mixed as to whether the drug truly treats stroke.^[1]

Mixed results

When tested on animal models, tirilazad protects brain tissue, and reduces any brain damage. On the contrary, the drug fails to treat, and even worsens a stroke when studied on a human being.

Usage in treatment of stroke

Tirilazad currently has no usage in the clinical treatment of stroke.

References

↑ "Tirilazad for acute ischaemic stroke". Retrieved 2007-07-28.

Template:Other nervous system drugs Template:Piperazines

[1] "Tirilazad for acute ischaemic stroke". Retrieved 2007-07-28.

[1]

@@ Line 53: / Line 53: @@
 | synonyms = <small>(8''S'',10''S'',13''S'',14''S'',16''R'',17''S'')-17-[2-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]acetyl]-10,13,16-trimethyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[''a'']phenanthren-3-one</small>
 }}
+__NOTOC__
+{{SI}}
+{{CMG}}
+==Overview==
 '''Tirilazad''' is a drug proposed to treat acute ischaemic [[stroke]], however results are mixed as to whether the drug truly treats stroke.<ref>{{cite web |url=http://www.cochrane.org/reviews/en/ab002087.html |title=Tirilazad for acute ischaemic stroke |accessdate=2007-07-28 |format= |work=}}</ref>
@@ Line 61: / Line 65: @@
 Tirilazad currently has no usage in the clinical treatment of stroke.
 ==References==
-{{reflist}}
+{{reflist|2}}
 {{Other nervous system drugs}}
@@ Line 69: / Line 73: @@
 [[Category:Pyrimidines]]
 [[Category:Pyrrolidines]]
+[[Category:Drug]]
-{{nervous-system-drug-stub}}