Vapreotide: Difference between revisions

Vapreotide
Clinical data
Trade names	Sanvar
Synonyms	Octastatin
ATC code	H01CB04 (WHO) ;
Pharmacokinetic data
Elimination half-life	30 minutes
Identifiers
	IUPAC name 2-Amino-N-[10-(4-aminobutyl)-4-{[1-carbamoyl-2-(1H-indol-2-yl)ethyl]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide;
CAS Number	103222-11-3;
PubChem CID	23725064;
PubChem SID	46506923;
DrugBank	DB04894;
ChemSpider	64425;
UNII	2PK59M9GFF;
KEGG	D06281;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C57H70N12O9S2
Molar mass	1131.37 g/mol
3D model (JSmol)	Interactive image;
Density	1.4 g/cm3
Boiling point	1,540.9 °C (2,805.62 °F)
	SMILES C(C)C1NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=C2C=CC=C3)NC(=O)C(CC2=CC=C(O)C=C2)NC(=O)C(CSSCC(NC1=O)C(=O)NC(CC1=CC2=C(N1)C=CC=C2)C(N)=O)NC(=O)C(N)CC1=CC=CC=C1;

Revision as of 19:02, 7 April 2015

Vapreotide (Sanvar) is a synthetic somatostatin analog. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea.^[1]

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 {{Drugbox
 | IUPAC_name = 2-Amino-''N''-[10-(4-aminobutyl)-4-{[1-carbamoyl-2-(1''H''-indol-2-yl)ethyl]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-(1''H''-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-(propan-2-yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide
-| image =  Vapreotide.svg
+| image =  Vapreotide.png
 | width =  200
 | alt =
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 {{Pituitary and hypothalamic hormones and analogues}}
-[[Category:Antineoplastic drugs]]
+[[Category:Drug]]
 [[Category:Lactams]]
 [[Category:Peptides]]
 [[Category:Hormonal agents]]
-{{systemic-hormonal-drug-stub}}