Racecadotril: Difference between revisions
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Latest revision as of 17:02, 20 August 2015
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Routes of administration | Oral |
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E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C21H23NO4S |
Molar mass | 385.47662 g/mol |
WikiDoc Resources for Racecadotril |
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Most recent articles on Racecadotril Most cited articles on Racecadotril |
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Powerpoint slides on Racecadotril |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Racecadotril at Clinical Trials.gov Clinical Trials on Racecadotril at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Racecadotril
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Definitions |
Patient Resources / Community |
Patient resources on Racecadotril Discussion groups on Racecadotril Patient Handouts on Racecadotril Directions to Hospitals Treating Racecadotril Risk calculators and risk factors for Racecadotril
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Healthcare Provider Resources |
Causes & Risk Factors for Racecadotril |
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Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Racecadotril is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.[1] Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine.[2] It is available in France (where it was first introduced in 1993 and is widely used) and other European countries, as well as most of South America and some South East Asian countries, but not in the United States. It is sold under the tradename Hidrasec.
A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy.[3]
References
- ↑ Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35. PMID 10804038
- ↑ (2001) "Racecadotril: an Antidiarrhoeal Suitable for Use in Infants and Young Children". Drug Ther Perspect 17 (8): 1–5. Free full text with registration at Medscape
- ↑ Salazar-Lindo E, Santisteban-Ponce J, Chea-Woo E, Gutierrez M (2000). "Racecadotril in the treatment of acute watery diarrhea in children". N. Engl. J. Med. 343 (7): 463–7. PMID 10944563.
See Also
Template:Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
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- Enkephalinase inhibitors