Oxatomide: Difference between revisions
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==Overview== | |||
'''Oxatomide''' (R35443) is a [[first-generation antihistamine]] of the [[phenylpiperazine]] class.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> It was discovered at [[Janssen Pharmaceutica]] in 1975. Oxatomide lacks any [[anticholinergic]] effects.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> In addition to its [[H1 receptor|H<sub>1</sub> receptor]] [[receptor_antagonist|antagonism]], it also possesses [[antiserotonergic]] actions.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> | '''Oxatomide''' (R35443) is a [[first-generation antihistamine]] of the [[phenylpiperazine]] class.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> It was discovered at [[Janssen Pharmaceutica]] in 1975. Oxatomide lacks any [[anticholinergic]] effects.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> In addition to its [[H1 receptor|H<sub>1</sub> receptor]] [[receptor_antagonist|antagonism]], it also possesses [[antiserotonergic]] actions.<ref name="pmid6138301">{{cite journal | author = Ohmori K, Ishii H, Nito M, Shuto K, Nakamizo N | title = [Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators] | language = Japanese | journal = Nippon Yakurigaku Zasshi. Folia Pharmacologica Japonica | volume = 81 | issue = 5 | pages = 399–409 |date=May 1983 | pmid = 6138301 | doi = 10.1254/fpj.81.399| url = }}</ref> | ||
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==References== | ==References== | ||
{{Reflist}} | {{Reflist|2}} | ||
{{Antihistamines}} | {{Antihistamines}} | ||
[[Category:H1 receptor antagonists]] | [[Category:H1 receptor antagonists]] | ||
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[[Category:Ureas]] | [[Category:Ureas]] | ||
[[Category:Lactams]] | [[Category:Lactams]] | ||
[[Category: | [[Category:Drug]] | ||
Latest revision as of 15:28, 10 April 2015
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| Trade names | Tinset, Cedlips, Atoxan |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C27H30N4O |
| Molar mass | 426.553 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Oxatomide (R35443) is a first-generation antihistamine of the phenylpiperazine class.[1] It was discovered at Janssen Pharmaceutica in 1975. Oxatomide lacks any anticholinergic effects.[1] In addition to its H1 receptor antagonism, it also possesses antiserotonergic actions.[1]
See also
References
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- Pages with script errors
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- CS1 maint: Unrecognized language
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- H1 receptor antagonists
- Piperazines
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