Flumetasone: Difference between revisions
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==Overview== | ==Overview== | ||
'''Flumethasone''' (usually as the [[pivalic acid]] [[ester]] '''flumethasone pivalate''', trade name '''Locacorten''' or '''Locorten''') is a [[corticosteroid]] for topical use. It is available in combination with [[clioquinol]], under the trade name '''Locacorten-Vioform''' (in some countries Locorten-Vioform), for the treatment of [[otitis externa]] and [[otomycosis]]. | '''Flumethasone''' (usually as the [[pivalic acid]] [[ester]] '''flumethasone pivalate''', trade name '''Locacorten''' or '''Locorten''') is a [[corticosteroid]] for topical use. It is available in combination with [[clioquinol]], under the trade name '''Locacorten-Vioform''' (in some countries Locorten-Vioform), for the treatment of [[otitis externa]] and [[otomycosis]]. | ||
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[[Category:Glucocorticoids]] | [[Category:Glucocorticoids]] | ||
[[Category:Organofluorides]] | [[Category:Organofluorides]] | ||
[[Category:Drug]] | [[Category:Drug]] | ||
Revision as of 20:50, 10 April 2015
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| Clinical data | |
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| Synonyms | (6S,8S,9S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Routes of administration | Topical |
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| Pharmacokinetic data | |
| Metabolism | Hepatic, CYP3A4-mediated |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C22H28F2O5 |
| Molar mass | 410.452 g/mol |
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Ongoing Trials on Flumetasone at Clinical Trials.gov Clinical Trials on Flumetasone at Google
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US National Guidelines Clearinghouse on Flumetasone
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Patient resources on Flumetasone Discussion groups on Flumetasone Patient Handouts on Flumetasone Directions to Hospitals Treating Flumetasone Risk calculators and risk factors for Flumetasone
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Causes & Risk Factors for Flumetasone |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Flumethasone (usually as the pivalic acid ester flumethasone pivalate, trade name Locacorten or Locorten) is a corticosteroid for topical use. It is available in combination with clioquinol, under the trade name Locacorten-Vioform (in some countries Locorten-Vioform), for the treatment of otitis externa and otomycosis.
Flumethasone shows fully 420 times the potency of cortisone in an animal model for anti-inflammatory activity.
Synthesis
See also
References
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- Articles with changed EBI identifier
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- Drugs with no legal status
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- Glucocorticoids
- Organofluorides
- Drug