Magnesium gluconate: Difference between revisions
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| ImageFile = magnesium gluconate. | | ImageFile = magnesium gluconate.png | ||
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| IUPACName = Magnesium bis[(2''R'',3''S'',4''R'',5''R'')-2,3,4,5,6-pentahydroxyhexanoate] | | IUPACName = Magnesium bis[(2''R'',3''S'',4''R'',5''R'')-2,3,4,5,6-pentahydroxyhexanoate] | ||
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==Overview== | ==Overview== | ||
'''Magnesium gluconate''' is a [[Compound (chemistry)|compound]] with formula MgC<sub>12</sub>H<sub>22</sub>O<sub>14</sub>. It is the [[magnesium]] [[salt]] of [[gluconic acid]]. | '''Magnesium gluconate''' is a [[Compound (chemistry)|compound]] with formula MgC<sub>12</sub>H<sub>22</sub>O<sub>14</sub>. It is the [[magnesium]] [[salt]] of [[gluconic acid]]. | ||
According to scientific research, Magnesium gluconate shows the highest level of [[bioavailability]] of any magnesium salt and is recommended as the optimal salt for human supplementation although of the 10 salts studied, all increased Magnesium levels significantly. | According to scientific research, Magnesium gluconate shows the highest level of [[bioavailability]] of any magnesium salt and is recommended as the optimal salt for human supplementation although of the 10 salts studied, all increased Magnesium levels significantly. | ||
It has [[E number]] "E580". | It has [[E number]] "E580". | ||
==Use in Medicine== | ==Use in Medicine== | ||
There are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of [[glucose]], so it was suggested that it may affect the energy metabolism of [[mitochondria]]. | There are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of [[glucose]], so it was suggested that it may affect the energy metabolism of [[mitochondria]]. In Ukraine, magnesium gluconate, together with [[potassium gluconate]] in the drug Rhythmocor is used to treat heart disease. Pilot studies have shown efficacy in various cardiac arrhythmia. Whether these effects are from the influence of gluconic acid on the metabolism of the heart or from the influence of magnesium and potassium on osmotic pressure is unknown. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Magnesium compounds]] | [[Category:Magnesium compounds]] | ||
[[Category:Drug]] | [[Category:Drug]] | ||
Revision as of 17:39, 13 April 2015
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| Names | |
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| IUPAC name
Magnesium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). |
PubChem CID
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| Properties | |
| C12H22MgO14 | |
| Molar mass | 414.60 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Magnesium gluconate is a compound with formula MgC12H22O14. It is the magnesium salt of gluconic acid.
According to scientific research, Magnesium gluconate shows the highest level of bioavailability of any magnesium salt and is recommended as the optimal salt for human supplementation although of the 10 salts studied, all increased Magnesium levels significantly.
It has E number "E580".
Use in Medicine
There are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of glucose, so it was suggested that it may affect the energy metabolism of mitochondria. In Ukraine, magnesium gluconate, together with potassium gluconate in the drug Rhythmocor is used to treat heart disease. Pilot studies have shown efficacy in various cardiac arrhythmia. Whether these effects are from the influence of gluconic acid on the metabolism of the heart or from the influence of magnesium and potassium on osmotic pressure is unknown.