Sandbox cdi: Difference between revisions
Jump to navigation
Jump to search
Gerald Chi (talk | contribs) mNo edit summary |
Gerald Chi (talk | contribs) mNo edit summary |
||
| Line 36: | Line 36: | ||
==Overview== | ==Overview== | ||
''Clostridium difficile'' infection is the most common infectious cause of nosocomial diarrhea. Clinical presentation ranges across a broad spectrum from asymptomatic carriage, to diarrheal illness, to complicated disease hallmarked by pseudomembranous colitis, toxic megacolon, or bowel perforation. Diagnosis is established by the presence of clinical features coupled with positive stool tests or endoscopic findings. Therapeutic approach and antibiotic choice should be stratified according to severity of disease and risk of recurrence. | |||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
Each of the following criteria must be present to fulfill the case definition for ''C. difficile'' infection: | |||
* The presence of diarrhea, defined as passage of 3 or more unformed stools in 24 or fewer consecutive hours {{and}} | |||
* A stool test positive for the presence of ''C. difficile'' organisms, toxins, or genes {{or}} colonoscopic or histopathologic findings demonstrating pseudomembranous colitis. | |||
==Classification== | ==Classification== | ||
| Line 71: | Line 67: | ||
==Dos and Don'ts== | ==Dos and Don'ts== | ||
=== | ===Dos=== | ||
Revision as of 02:36, 25 April 2015
| Clostridium difficile infection |
|
|
|
Dos and Don'ts |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Clostridium difficile infection is the most common infectious cause of nosocomial diarrhea. Clinical presentation ranges across a broad spectrum from asymptomatic carriage, to diarrheal illness, to complicated disease hallmarked by pseudomembranous colitis, toxic megacolon, or bowel perforation. Diagnosis is established by the presence of clinical features coupled with positive stool tests or endoscopic findings. Therapeutic approach and antibiotic choice should be stratified according to severity of disease and risk of recurrence.
Diagnostic Criteria
Each of the following criteria must be present to fulfill the case definition for C. difficile infection:
- The presence of diarrhea, defined as passage of 3 or more unformed stools in 24 or fewer consecutive hours AND
- A stool test positive for the presence of C. difficile organisms, toxins, or genes OR colonoscopic or histopathologic findings demonstrating pseudomembranous colitis.