Premature ovarian failure medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Medical Therapy

Treatments of premature ovarian failure include estrogen therapy to release symptoms and tresatments on the complications.

• Estrogen therapy: The goal of estrogen therapy is to help prevent osteoporosis and relieve symptoms of estrogen deficiency, such as vaginal dryness and hot flashes. The doctors usually prescribe both estrogen and progesterone to protect the lining of your uterus from precancerous changes that may result if you take estrogen alone. According to the association on hormone replacement therapy and cardiovascular diseases and breast cancer incidence, doctors prefer that the benefits of hormone replacement therapy usually outweigh the potential risks in young women with premature ovarian failure .
• Calcium and vitamin D supplements: These treatments are important for bone health and help decrease the risk of development of osteoporosis.
• Treatments on infertility: Infertility is a common complication of premature ovarian failure. For women with this disorder, the way of pregnancy is fertilized in vitro by using a donor's eggs.

Contraindicated medications

Primary ovarian failure is considered an absolute contraindication to the use of the following medications:

• Choriogonadotropin alfa
• Urofollitropin