Class III recommendations in guidelines for cardiovascular medicine

Class III Recommendations in Guidelines for Cardiovascular Medicine
Main Page
List of All Class III Recommendations
Organized by Guideline
Guideline Keywords
Year of Guideline Publication
Organized by Level of Evidence
LOE: A
LOE: B
LOE: C
Unclassified LOE
List of Guidelines

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Aparna Vuppala, M.B.B.S. [2]

Class III Recommendations in Guidelines for Cardiovascular Medicine

• Class III recommendations are defined as conditions for which there is evidence and/or general agreement that the procedure or treatment is not useful/effective and in some cases may be harmful.

• Class III recommendations may be further classified according to the level of evidence (LOE):

• • LOE A: Defined as evidence obtained from either multiple populations, multiple randomized clinical trials, or meta-analyses of randomized clinical trials.

• • LOE B: Defined as evidence obtained from either a limited number of populations, a single randomized clinical trial, or meta-analyses of non-randomized studies.

• • LOE C: Defined as evidence obtained from either a very limited number of populations, consensus opinion of experts, case studies, or standard of care.

• Class III recommendations may also be classified according to the reasoning behind the development of the recommendation, which may be due to evidence of no benefit or due to evidence of harm.