Sandbox Organ-Based Infections: Difference between revisions
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===Pharyngitis=== | ===Pharyngitis=== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,277: | Line 3,275: | ||
</li> | </li> | ||
==== | ====Diphtheria==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,286: | Line 3,284: | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | ||
</li> | </li> | ||
=== | ===Parapharyngeal space infection==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,297: | Line 3,295: | ||
</li> | </li> | ||
==== | ====Lemierre's syndrome==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,307: | Line 3,305: | ||
</li> | </li> | ||
==== | ====Streptococcal pharyngitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
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* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | ||
</li> | </li> | ||
==== | ====Jugular vein phlebitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,326: | Line 3,324: | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | ||
</li> | </li> | ||
=== | ===Epiglottitis=== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
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</li> | </li> | ||
==== | ====Laryngitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,347: | Line 3,345: | ||
</li> | </li> | ||
==== | ====Tonsillitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,357: | Line 3,355: | ||
</li> | </li> | ||
===Otitis media=== | |||
====Otitis media, Acute==== | ====Otitis media, Acute==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
| Line 3,397: | Line 3,397: | ||
</li> | </li> | ||
===Sinusitis=== | |||
====Sinusitis, Acute==== | ====Sinusitis, Acute==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
| Line 3,436: | Line 3,438: | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | ||
</li> | </li> | ||
===Stomatitis=== | |||
==== | ====Aphthous Stomatitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,447: | Line 3,451: | ||
</li> | </li> | ||
==== | ====Buccal cellulitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,457: | Line 3,461: | ||
</li> | </li> | ||
==== | ====Gingivostomatitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,467: | Line 3,471: | ||
</li> | </li> | ||
==== | ====Herpetic stomatitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,477: | Line 3,481: | ||
</li> | </li> | ||
==== | ====Ludwig's angina==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
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</li> | </li> | ||
==== | ====Submandibular space infection==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
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</li> | </li> | ||
==== | ====Ulcerative gingivitis==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
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</li> | </li> | ||
==== | ====Vincent's angina==== | ||
{{Rx|Preferred Regimen}} | {{Rx|Preferred Regimen}} | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration {{and}} | ||
| Line 3,516: | Line 3,520: | ||
* '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | * '''[[Drug]]''' DosageRouteFrequencyDuration {{or}} '''[[Drug]]''' DosageRouteFrequencyDuration | ||
</li> | </li> | ||
==Head and neck== | ==Head and neck== | ||
Revision as of 06:35, 10 May 2015
Musculoskeletal
Osteomyelitis
Candidal osteomyelitis
- Fluconazole 400 mg (6 mg/kg) IV/po daily OR Lipid-based Amphotericin B 3-5 mg/kg daily for two weeks, followed by Fluconazole
- Caspofungin 70 mg loading dose, then 50 mg/day IV OR Micafungin 100 mg/day IV or Anidulafungin 200 mg IV loading dose, then 100 mg/day IV
Chronic osteomyelitis
- Systemic antibiotics per culture and susceptibility results AND
- Surgical debridement
Contiguous with vascular insufficiency
- Systemic antibiotics per culture and susceptibility results AND
- Surgical debridement AND
- Revascularization if possible
Contiguous without vascular insufficiency
- Vancomycin 1 gm IV q12h AND
- Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h
- Linezolid 600 mg po/IV bid AND
- Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h
- Ciprofloxacin 750 mg po bid OR Linezolid 600 mg po/IV bid
- Vancomycin 15-20 mg/kg IV q8-12h targeting trough concentrations of 15-20 mg/L
- Ciprofloxacin 750 mg po bid OR Levofloxacin 750 mg po once daily if susceptible AND
- Rifampin 300-450 mg po bid OR Rifampin 600 mg po once daily if susceptible
Diabetic foot
- Levofloxacin 750 mg IV/PO q24h OR Cefoxitin 1 g IV q4h (or 2 g IV q6–8h) OR Ceftriaxone 1–2 g/day IV/IM q12–24h OR Ampicillin-Sulbactam 1.5–3 g IV/IM q6h OR Moxifloxacin 400 mg IV/PO q24h OR Ertapenem 1 g IV/IM q24h OR Tigecycline 100 mg IV, then 50 mg IV q12h OR Imipenem-Cilastatin 0.5–1 g IV q6–8h
- Linezolid 600 mg IV/PO q12h OR Daptomycin 4 mg/kg IV q24h OR Vancomycin 15–20 mg/kg IV q8–12h (trough: 10–20 mg/L)
- Piperacillin–Tazobactam 3.375 g IV q6–8h
- (Vancomycin 15–20 mg/kg IV q8–12h OR Linezolid 600 mg IV/PO q12h OR Daptomycin 4 mg/kg IV q24h) AND
- (Piperacillin–Tazobactam 3.375 g IV q6–8h OR Imipenem-Cilastatin 0.5–1 g IV q6–8h OR Ertapenem 1 g IV/IM q24h OR Meropenem 1 g IV/IM q24h) OR (Metronidazole 15 mg/kg IV, then 7.5 mg/kg IV q6h PLUS Ceftazidime 2 g IV q8h OR Cefepime 2 g IV q8h OR Aztreonam 2 g IV q6–8h)
Foot bone
- Ciprofloxacin 750 mg po bid OR Levofloxacin 750 mg po q24h
- Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q8h OR Meropenem 1 gm IV q8h