Sandbox ID Genitourinary

• Chancroid

• Preferred regimen: Azithromycin 1 g orally in a single dose OR Ceftriaxone 250 mg intramuscularly (IM) in a single dose) OR Ciprofloxacin 500 mg orally twice a day for 3 days OR Erythromycin base 500 mg orally three times a day for 7 days
• Ciprofloxacin is contraindicated for pregnant and lactating women.

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• Gonococcal infections

• Uncomplicated Gonococcal Infections of the Cervix, Urethra, and Rectum

• Preferred regimen: Ceftriaxone 250 mg intramuscularly AND (Azithromycin 1 g orally as a single dose OR Doxycycline 100 mg orally twice daily for 7 days)
• Alternative regimen: Cefuroxime 1 g orally

• Uncomplicated Gonococcal Infections of the Pharynx

• Preferred regimen: Ceftriaxone 250 mg IM in a single dose AND (Azithromycin 1 g orally as a single dose OR Doxycycline 100 mg orally twice daily for 7 days)

• Gonococcal Conjunctivitis

• Preferred regimen: Ceftriaxone 1 g IM in a single dose

• Disseminated Gonococcal Infection (DGI)

• Preferred regimen: Ceftriaxone 1 g IV/IM every 24 hours
• Alternative regimen: Cefotaxime 1 g IV every 8 hours OR Ceftizoxime 1 g IV every 8 hours
• All of the preceding regimens should be continued for 24--48 hours after improvement begins, at which time therapy can be switched to cefixime 400 mg orally twice daily to complete at least 1 week of antimicrobial therapy. No treatment failures have been reported with the recommended regimens.

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