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! Pathogen !! Immunocompetent patients !! Immunocompromised patients
! Pathogen !! Immunocompetent patients !! Immunocompromised patients
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|Shigella species || TMP-SMZ, 160 and 800 mg, respectively (pediatric dose, 5 and 25 mg/kg, respectively) b.i.d. 3 3 d (if susceptiblea ) or fluoroquinoloneb (e.g., 300 mg ofloxacin, 400 mg norfloxacin [186], or 500 mg ciprofloxacin b.i.d. 3 3 d) (A-I) [117–121]; nalidixic acid, 55 mg/kg/d (pediatric) or 1 g/d (adults) 3 5 d [220] or ceftriaxone [79]; azithromycin [121] || 3 7–10 d
|Shigella species || [[TMP-SMZ]], 160 and 800 mg, respectively (pediatric dose, 5 and 25 mg/kg, respectively) b.i.d. 3 3 d (if susceptiblea ) or [[fluoroquinoloneb]] (e.g., 300 mg ofloxacin, 400 mg norfloxacin [186], or 500 mg ciprofloxacin b.i.d. 3 3 d); [[nalidixic acid]], 55 mg/kg/d (pediatric) or 1 g/d (adults) 3 5 d [220] or [[ceftriaxone]] azithromycin [121] || 3 7–10 d
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|Non-typhi species of Salmonella || Not recommended routinely (E-I) [59,60], but if severe or patient is !6 mo or 150 y old or has prostheses, valvular heart disease, severe atherosclerosis, malignancy, or uremia, TMP-SMZ (if susceptible) or fluoroquinoloneb as above, b.i.d. 3 5–7 d (B-III) [29, 132, 221]; ceftriaxone, 100 mg/kg/d in 1 or 2 divided doses [222 ||  14 d (or longer if relapsing)
|Non-typhi species of Salmonella || Not recommended routinely (E-I) [59,60], but if severe or patient is !6 mo or 150 y old or has prostheses, valvular heart disease, severe atherosclerosis, malignancy, or uremia, [[TMP-SMZ]] (if susceptible) or [[fluoroquinolone]] as above, b.i.d. 3 5–7 d; ceftriaxone, 100 mg/kg/d in 1 or 2 divided doses ||  14 d (or longer if relapsing)


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Revision as of 17:25, 29 May 2015

The table's caption
Column heading 1 Column heading 2 Column heading 3
Row heading 1 Cell 2 Cell 3
Row heading A Cell B Cell C
GI infection
Pathogen Immunocompetent patients Immunocompromised patients
Shigella species TMP-SMZ, 160 and 800 mg, respectively (pediatric dose, 5 and 25 mg/kg, respectively) b.i.d. 3 3 d (if susceptiblea ) or fluoroquinoloneb (e.g., 300 mg ofloxacin, 400 mg norfloxacin [186], or 500 mg ciprofloxacin b.i.d. 3 3 d); nalidixic acid, 55 mg/kg/d (pediatric) or 1 g/d (adults) 3 5 d [220] or ceftriaxone azithromycin [121] 3 7–10 d
Non-typhi species of Salmonella Not recommended routinely (E-I) [59,60], but if severe or patient is !6 mo or 150 y old or has prostheses, valvular heart disease, severe atherosclerosis, malignancy, or uremia, TMP-SMZ (if susceptible) or fluoroquinolone as above, b.i.d. 3 5–7 d; ceftriaxone, 100 mg/kg/d in 1 or 2 divided doses 14 d (or longer if relapsing)