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===Conjunctivitis===
===Conjunctivitis===


* Conjunctivitis, acute<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=PMC4049531 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468  }} </ref>
* Conjunctivitis, acute<ref>{{Cite journal| doi = 10.1001/jama.2013.280318| issn = 1538-3598| volume = 310| issue = 16| pages = 1721–1729| last1 = Azari| first1 = Amir A.| last2 = Barney| first2 = Neal P.| title = Conjunctivitis: a systematic review of diagnosis and treatment| journal = JAMA| date = 2013-10-23| pmid = 24150468| pmc = PMC4049531}}</ref>
:* Empiric antimicrobial therapy, bacterial
::* Preferred regimen (1): [[Gentamicin]] ointment qid for 1 week {{or}} [[Gentamicin]] solution 1-2 drops qid for 1 week {{or}} [[Tobramycin]] ointment tid for 1 week
::* Preferred regimen (2): [[Besifloxacin]] solution 1 drop 3 times for 1 week {{or}} [[Ciprofloxacin]] ointment tid for 1 week {{or}} [[Ciprofloxacin]] solution 1-2 drops topical qid for 1 week {{or}} [[Gatifloxacin]] solution tid for 1 week {{or}} [[Levofloxacin]] solution 1-2 drops qid for 1 week {{or}} [[Moxifloxacin]] solution tid for 1 week {{or}} [[Ofloxacin]] solution 1-2 drops qid for 1 week
::* Preferred regimen (3): [[Azithromycin]] ointment bid for 2 days, then 1 drop qd for 5 days {{or}} [[Erythromycin]] ointment qid for 1 week
::* Preferred regimen (4): [[Sulfacetamide]] ointment qid and at bedtime for 1 week {{or}} [[Sulfacetamide]] solution 1-2 drops q2-3h for 1 week
::* Preferred regimen (5): [[Trimethoprim]]/[[Polymyxin B]] solution 1 or 2 drops qid for 1 week
::: Note: Topical steroids are not recommended for bacterial conjunctivitis.


:* Culture-directed antimicrobial therapy
:* Bacterial conjunctivitis
::* '''Methicillin-resistant Staphylococcus aureus'''
::* Empiric antimicrobial therapy,
:::* Preferred regimen: [[Vancomycin]] ointment 1% qid
:::* Preferred regimen (1): [[Gentamicin]] ointment qid for 1 week {{or}} [[Gentamicin]] solution 1-2 drops qid for 1 week {{or}} [[Tobramycin]] ointment tid for 1 week
:::* Preferred regimen (2): [[Besifloxacin]] solution 1 drop 3 times for 1 week {{or}} [[Ciprofloxacin]] ointment tid for 1 week {{or}} [[Ciprofloxacin]] solution 1-2 drops topical qid for 1 week {{or}} [[Gatifloxacin]] solution tid for 1 week {{or}} [[Levofloxacin]] solution 1-2 drops qid for 1 week {{or}} [[Moxifloxacin]] solution tid for 1 week {{or}} [[Ofloxacin]] solution 1-2 drops qid for 1 week
:::* Preferred regimen (3): [[Azithromycin]] ointment bid for 2 days, then 1 drop qd for 5 days {{or}} [[Erythromycin]] ointment qid for 1 week
:::* Preferred regimen (4): [[Sulfacetamide]] ointment qid and at bedtime for 1 week {{or}} [[Sulfacetamide]] solution 1-2 drops q2-3h for 1 week
:::* Preferred regimen (5): [[Trimethoprim]]/[[Polymyxin B]] solution 1 or 2 drops qid for 1 week
:::: Note: Topical steroids are not recommended for bacterial conjunctivitis.


:* Pathogen-directed antimicrobial therapy
::* '''Chlamydia trachomatis'''
::* '''Chlamydia trachomatis'''
:::* Inclusion conjunctivitis
:::* Inclusion conjunctivitis
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::::: Note: Dual therapy to cover Chlamydia is indicated.
::::: Note: Dual therapy to cover Chlamydia is indicated.


::* '''Herpes simplex virus'''
::* '''Staphylococcus aureus, methicillin-resistant (MRSA)'''
:::* Preferred regimen: [[Acyclovir]] 1 drop topical 9 times per day {{or}} [[Acyclovir]] 400 mg PO 5 times per day for 7-10 days {{or}} [[Valacyclovir]] 500 mg PO tid for 7-10 days
:::* Preferred regimen: [[Vancomycin]] ointment 1% qid
:::: Note: Topical steroids should be avoided.
 
::* Herpetic conjunctivitis
:::* '''Herpes simplex virus'''
::::* Preferred regimen: [[Acyclovir]] 1 drop topical 9 times per day {{or}} [[Acyclovir]] 400 mg PO 5 times per day for 7-10 days {{or}} [[Valacyclovir]] 500 mg PO tid for 7-10 days
::::: Note: Topical steroids should be avoided.


::* '''Varicella zoster virus'''
:::* '''Varicella zoster virus'''
:::* Preferred regimen: [[Acyclovir]] 800 mg PO 5 times per day for 7-10 days {{or}} [[Famciclovir]] 500 mg PO tid for 7-10 days {{or}} [[Valacyclovir]] 1000 mg PO tid for 7-10 days
::::* Preferred regimen: [[Acyclovir]] 800 mg PO 5 times per day for 7-10 days {{or}} [[Famciclovir]] 500 mg PO tid for 7-10 days {{or}} [[Valacyclovir]] 1000 mg PO tid for 7-10 days
:::: Note: Treatment usually consists of a combination of oral antivirals and topical steroids.
::::: Note: Treatment usually consists of a combination of oral antivirals and topical steroids.


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Revision as of 20:23, 2 June 2015

Conjunctivitis

  • Conjunctivitis, acute[1]
  • Bacterial conjunctivitis
  • Empiric antimicrobial therapy,
Note: Topical steroids are not recommended for bacterial conjunctivitis.
  • Pathogen-directed antimicrobial therapy
  • Chlamydia trachomatis
  • Inclusion conjunctivitis
  • Conjunctivitis secondary to trachoma
  • Neisseria gonorrhoeae
  • Hyperacute bacterial conjunctivitis, adult
Note: Dual therapy to cover Chlamydia is indicated.
  • Staphylococcus aureus, methicillin-resistant (MRSA)
  • Herpetic conjunctivitis
  • Herpes simplex virus
  • Preferred regimen: Acyclovir 1 drop topical 9 times per day OR Acyclovir 400 mg PO 5 times per day for 7-10 days OR Valacyclovir 500 mg PO tid for 7-10 days
Note: Topical steroids should be avoided.
  • Varicella zoster virus
Note: Treatment usually consists of a combination of oral antivirals and topical steroids.

Blepharitis

Endophthalmitis, bacterial

Endophthalmitis, bleb-related

Endophthalmitis, candidal

Endophthalmitis, chronic

Endophthalmitis, mold

Endophthalmitis, post-cataract surgery, acute

Endophthalmitis, post-cataract surgery, chronic

Endophthalmitis, post-tramatic

Keratitis, bacterial

Keratitis, fungal

Keratitis, protozoal

Keratitis, viral

Ocular syphilis

Ocular toxocariasis

Ocular toxoplasmosis

Ocular tuberculosis

Orbital cellulitis

Periocular Infection

Retinal necrosis, acute, CMV

Retinal necrosis, acute, HSV or VZV

Retinal necrosis, progressive outer, VZV

Retinitis, CMV

Stye

Uveitis, acute anterior

Uveitis, Lyme disease

References

  1. Azari, Amir A.; Barney, Neal P. (2013-10-23). "Conjunctivitis: a systematic review of diagnosis and treatment". JAMA. 310 (16): 1721–1729. doi:10.1001/jama.2013.280318. ISSN 1538-3598. PMC 4049531. PMID 24150468.