Sandbox g16: Difference between revisions
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* The safety, efficacy, and pharmacokinetics of abacavir have not been studied in patients with moderate or severe hepatic impairment; therefore, abacavir is contraindicated in these patients. | * The safety, efficacy, and pharmacokinetics of abacavir have not been studied in patients with moderate or severe hepatic impairment; therefore, abacavir is contraindicated in these patients. | ||
|- | |- | ||
| Atazanavir || | | Atazanavir | ||
| Antiviral agent | |||
| | |||
|- | |- | ||
| Caspofungin | | Caspofungin | ||
|- | |- | ||
| Ceftriaxone | | Ceftriaxone | ||
|- | |- | ||
| Chloramphenicol | | Chloramphenicol | ||
|- | |- | ||
| Clindamycin | | Clindamycin | ||
|- | |- | ||
| Darunavir | | Darunavir | ||
|- | |- | ||
| Delavirdine | | Delavirdine | ||
|- | |- | ||
| Efavirenz | | Efavirenz | ||
|- | |- | ||
| Enfuvirtide | | Enfuvirtide | ||
|- | |- | ||
| Fosamprenavir | | Fosamprenavir | ||
|- | |- | ||
| Fusidic acid | | Fusidic acid | ||
|- | |- | ||
| Indinavir | | Indinavir | ||
|- | |- | ||
| Isoniazid | | Isoniazid | ||
|- | |- | ||
| Itraconazole | | Itraconazole | ||
|- | |- | ||
| Lopinavir-Ritonavir | | Lopinavir-Ritonavir | ||
|- | |- | ||
| Metronidazole | | Metronidazole | ||
|- | |- | ||
| Nafcillin | | Nafcillin | ||
|- | |- | ||
| Nelfinavir | | Nelfinavir | ||
|- | |- | ||
| Nevirapine | | Nevirapine | ||
|- | |- | ||
| Quinupristin-Dalfopristin | | Quinupristin-Dalfopristin | ||
|- | |- | ||
| Rifabutin | | Rifabutin | ||
|- | |- | ||
| Rifampin | | Rifampin | ||
|- | |- | ||
| Rimantadine | | Rimantadine | ||
|- | |- | ||
| Ritonavir | | Ritonavir | ||
|- | |- | ||
| Telithromycin | | Telithromycin | ||
|- | |- | ||
| Tigecycline | | Tigecycline | ||
|- | |- | ||
| Tinidazole | | Tinidazole | ||
|- | |- | ||
| Voriconazole | | Voriconazole | ||
|} | |} | ||
Revision as of 03:30, 4 June 2015
Dosage adjustment in patients with hepatic disease Return to Top
Dosage adjustment may be required in the presence of hepatic disease for the following medications (consult FDA package insert for details):
| Antimicrobial Agent | Category | Recommendation |
|---|---|---|
| Abacavir | Antiviral agent |
|
| Atazanavir | Antiviral agent | |
| Caspofungin | ||
| Ceftriaxone | ||
| Chloramphenicol | ||
| Clindamycin | ||
| Darunavir | ||
| Delavirdine | ||
| Efavirenz | ||
| Enfuvirtide | ||
| Fosamprenavir | ||
| Fusidic acid | ||
| Indinavir | ||
| Isoniazid | ||
| Itraconazole | ||
| Lopinavir-Ritonavir | ||
| Metronidazole | ||
| Nafcillin | ||
| Nelfinavir | ||
| Nevirapine | ||
| Quinupristin-Dalfopristin | ||
| Rifabutin | ||
| Rifampin | ||
| Rimantadine | ||
| Ritonavir | ||
| Telithromycin | ||
| Tigecycline | ||
| Tinidazole | ||
| Voriconazole |