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:* Preferred regimen: [[Doxycycline]] 100 mg orally bid (or intravenously for those patients unable to take an oral medication) for 10 days | :* Preferred regimen: [[Doxycycline]] 100 mg orally bid (or intravenously for those patients unable to take an oral medication) for 10 days | ||
:* Alternative regimen: [[Rifampin]] 300 mg orally bid for 7–10 days (For patients with mild illness due to HGA who are not optimally suited for doxycycline treatment because of a history of drug allergy, pregnancy, or age | :* Alternative regimen: [[Rifampin]] 300 mg orally bid for 7–10 days (For patients with mild illness due to HGA who are not optimally suited for doxycycline treatment because of a history of drug allergy, pregnancy, or age <8 years) | ||
:* Pediatric regimen: [[Doxycycline]] 4 mg/kg per day in 2 divided doses (maximum of 100 mg per dose) given orally (or intravenously for children unable to take an oral medication); [[Rifampin]] 10 mg/kg bid for children (maximum of 300 mg per dose) | :* Pediatric regimen: [[Doxycycline]] 4 mg/kg per day in 2 divided doses (maximum of 100 mg per dose) given orally (or intravenously for children unable to take an oral medication); [[Rifampin]] 10 mg/kg bid for children (maximum of 300 mg per dose) | ||
: NOTE (1): Children ≥8 years of age may be treated with a 10-day course of [[Doxycycline]]; For severely ill children <8 years of age without concomitant Lyme disease, the panel recommended an abbreviated treatment course of 4–5 days | : NOTE (1): Children ≥8 years of age may be treated with a 10-day course of [[Doxycycline]]; For severely ill children <8 years of age without concomitant Lyme disease, the panel recommended an abbreviated treatment course of 4–5 days | ||
Revision as of 14:02, 16 June 2015
Anaplasmosis
- Human granulocytic anaplasmosis, suspected or symptomatic
- Preferred regimen: Doxycycline 100 mg orally bid (or intravenously for those patients unable to take an oral medication) for 10 days
- Alternative regimen: Rifampin 300 mg orally bid for 7–10 days (For patients with mild illness due to HGA who are not optimally suited for doxycycline treatment because of a history of drug allergy, pregnancy, or age <8 years)
- Pediatric regimen: Doxycycline 4 mg/kg per day in 2 divided doses (maximum of 100 mg per dose) given orally (or intravenously for children unable to take an oral medication); Rifampin 10 mg/kg bid for children (maximum of 300 mg per dose)
- NOTE (1): Children ≥8 years of age may be treated with a 10-day course of Doxycycline; For severely ill children <8 years of age without concomitant Lyme disease, the panel recommended an abbreviated treatment course of 4–5 days
- NOTE (2): If the child has concomitant Lyme disease, then Amoxicillin 50 mg/kg per day in 3 divided doses (maximum of 500 mg per dose) OR Cefuroxime axetil 30 mg/kg per day in 2 divided doses (maximum of 500 mg per dose) should be initiated at the conclusion of the course of Doxycycline to complete a 14-day total course of antibiotic therapy
- NOTE: Rifampin is not effective therapy for Lyme disease, patients coinfected with B. burgdorferi should also be treated with amoxicillin or cefuroxime axetil