Mycobacterium gordonae: Difference between revisions
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==Treatment== | ==Treatment== | ||
===Antimicrobial regimen=== | ===Antimicrobial regimen=== | ||
* Preferred regimen: [[Ethambutol]] {{or}} [[Rifabutin]] {{or}} [[Clarithromycin]] {{or}} [[Linezolid]] {{or}} [[Fluoroquinolones]] | * M. gordonae <ref>{{Cite journal| doi = 10.1164/rccm.200604-571ST| issn = 1073-449X| volume = 175| issue = 4| pages = 367–416| last1 = Griffith| first1 = David E.| last2 = Aksamit| first2 = Timothy| last3 = Brown-Elliott| first3 = Barbara A.| last4 = Catanzaro| first4 = Antonino| last5 = Daley| first5 = Charles| last6 = Gordin| first6 = Fred| last7 = Holland| first7 = Steven M.| last8 = Horsburgh| first8 = Robert| last9 = Huitt| first9 = Gwen| last10 = Iademarco| first10 = Michael F.| last11 = Iseman| first11 = Michael| last12 = Olivier| first12 = Kenneth| last13 = Ruoss| first13 = Stephen| last14 = von Reyn| first14 = C. Fordham| last15 = Wallace| first15 = Richard J.| last16 = Winthrop| first16 = Kevin| last17 = ATS Mycobacterial Diseases Subcommittee| last18 = American Thoracic Society| last19 = Infectious Disease Society of America| title = An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases| journal = American Journal of Respiratory and Critical Care Medicine| date = 2007-02-15| pmid = 17277290}}</ref> | ||
:* Preferred regimen: [[Ethambutol]] {{or}} [[Rifabutin]] {{or}} [[Clarithromycin]] {{or}} [[Linezolid]] {{or}} [[Fluoroquinolones]] | |||
==References== | ==References== |
Revision as of 18:09, 6 July 2015
Mycobacterium gordonae | ||||||||||||||
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Scientific classification | ||||||||||||||
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Binomial name | ||||||||||||||
Mycobacterium gordonae Bojalil et al. 1962, ATCC 14470 |
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Mycobacterium gordonae
Description
Gram-positive, nonmotile and moderate to long acid-fast rods.
- Commonly found in tap water and soil. Casual resident in human sputum and gastric lavage specimens.
Colony characteristics
- Smooth, with yellow or orange scotochromogenic colonies. Even though they are scotochromogenic pigment is intensified by growing in continuous light.
Physiology
- Growth on Löwenstein-Jensen medium and Middlebrook 7H10 agar within 7 or more days at 37°C (optimal 25°C).
- Does not grow in the presence of ethambutol (1mg/l), isoniazid (10mg/l) and sodium chloride (5%).
Differential characteristics
- A commercial hybridisation assay (AccuProbe) to identify M. gordonae exists.
- Intraspecies variability in 16S rDNA sequences
Pathogenesis
- Rarely if ever implicated in disease processes unless patients are immunocompromised.
- Biosafety level 1
Type Strain
Strain ATCC 14470 = CCUG 21801 = CCUG 21811 = CIP 104529 = DSM 44160 = JCM 6382 = NCTC 10267.
Treatment
Antimicrobial regimen
- M. gordonae [1]
- Preferred regimen: Ethambutol OR Rifabutin OR Clarithromycin OR Linezolid OR Fluoroquinolones
References
- ↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). "An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases". American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.
- Bojalil et al. 1962. Adansonian classification of mycobacteria. Journal of General Microbiology, 28, 333-346.