Onchocerciasis: Difference between revisions
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[[Onchocerciasis medical therapy|Medical Therapy]] | [[Onchocerciasis primary prevention|Primary Prevention]] | [[Onchocerciasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Onchocerciasis future or investigational therapies|Future or Investigational Therapies]] | [[Onchocerciasis medical therapy|Medical Therapy]] | [[Onchocerciasis primary prevention|Primary Prevention]] | [[Onchocerciasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Onchocerciasis future or investigational therapies|Future or Investigational Therapies]] | ||
===Antimicrobial therapy=== | ===Antimicrobial therapy=== | ||
:* '''Onchoceria volvulus cutaneous filariasis (river blindness) treatment'''{{cite book | last = Gilbert | first = David | title = The Sanford guide to antimicrobial therapy 2014 | publisher = Antimicrobial Therapy | location = Sperryville, Va | year = 2014 | isbn = 978-1930808782 }} | |||
::* Preferred regimen: [[Ivermectin]] Single dose of 150 mcg/kg po; repeat q6-12months until asymptomatic. | |||
::* Alternative regimen: If [[Ivermectin]] fails, consider [[Suramin]]. | |||
::* Note (1): Onchocercia and Loa loa may both be present. Check peripheral smear; if Loa loa microfilaria present, treat onchocercia first with [[Ivermectin]] before [[Diethylcarbamazine]] (DEC) for Loa loa. | |||
::* Note (2): Retreatment for microfilaremia often necessary q6-12 months as demonstrated by repeat blood smear or antigen testing. | |||
::* Note (3): Do not use [[Diethylcarbamazine]] (DEC) in Onchocerca volvulus due to increased risks of precipitating blindness. | |||
Revision as of 16:21, 29 July 2015
Onchocerca volvulus | ||||||||||||||
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O. volvulus, the causative agent of river blindness.
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Scientific classification | ||||||||||||||
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Binomial name | ||||||||||||||
Onchocerca volvulus Bickel 1982 |
Onchocerciasis Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Onchocerciasis On the Web |
American Roentgen Ray Society Images of Onchocerciasis |
For patient information, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]
Synonyms and keywords: Onchocercosis; river blindness; Robles disease; onchocerca volvulus infection
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Onchocerciasis from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Antimicrobial therapy
- Onchoceria volvulus cutaneous filariasis (river blindness) treatmentGilbert, David (2014). The Sanford guide to antimicrobial therapy 2014. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808782.
- Preferred regimen: Ivermectin Single dose of 150 mcg/kg po; repeat q6-12months until asymptomatic.
- Alternative regimen: If Ivermectin fails, consider Suramin.
- Note (1): Onchocercia and Loa loa may both be present. Check peripheral smear; if Loa loa microfilaria present, treat onchocercia first with Ivermectin before Diethylcarbamazine (DEC) for Loa loa.
- Note (2): Retreatment for microfilaremia often necessary q6-12 months as demonstrated by repeat blood smear or antigen testing.
- Note (3): Do not use Diethylcarbamazine (DEC) in Onchocerca volvulus due to increased risks of precipitating blindness.