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=[http://www.wikidoc.org/index.php/Differentiating_(disease_name)_from_other_diseases_page Instructions]=
=[http://www.wikidoc.org/index.php/Differentiating_(disease_name)_from_other_diseases_page Instructions]=
=Example=


==Differentiating Legionnaires' disease from other diseases==
==Differentiating Legionnaires' disease from other diseases==
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{{ddx1|Viral pneumonia}}
{{ddx1|Viral pneumonia}}


==Findings suggestive of Legionnaires' disease==
----


===Clinical manifestations===
{{ddx|Legionnaires' disease}}
 
=====Clinical manifestations=====
* High grade fever
* High grade fever
* Dry cough
* Dry cough
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* Adult respiratory distress syndrome
* Adult respiratory distress syndrome


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Legionella urinary antigen positive
* Legionella urinary antigen positive
* Alveolar consolidation on chest radiograph
* Alveolar consolidation on chest radiograph
* Lobar consolidation on chest radiograph
* Lobar consolidation on chest radiograph


==Findings suggestive of Acute interstitial pneumonia==
----


===Clinical manifestations===
{{ddx|Acute interstitial pneumonia}}
 
=====Clinical manifestations=====
* Dry cough
* Dry cough
* Progressive dyspnea
* Progressive dyspnea
* Adult respiratory distress syndrome
* Adult respiratory distress syndrome


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Disseminated consolidation on chest radiograph
* Disseminated consolidation on chest radiograph
* Interstitial infiltrate on chest radiograph
* Interstitial infiltrate on chest radiograph
* Increased uptake on Gallium scan
* Increased uptake on Gallium scan


==Findings suggestive of Mycoplasma pneumonia==
-----


===Clinical manifestations===
{{ddx|Mycoplasma pneumonia}}
 
=====Clinical manifestations=====
* Dry cough
* Dry cough
* Pleuritic chest pain
* Pleuritic chest pain
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* Bronchial breath sounds
* Bronchial breath sounds


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Lymphocytosis
* Lymphocytosis
* Cold agglutinins positive
* Cold agglutinins positive
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* Lobar consolidation on chest radiograph
* Lobar consolidation on chest radiograph


==Findings suggestive of Pneumococcal pneumonia==
----


===Clinical manifestations===
{{ddx|Pneumococcal pneumonia}}
 
=====Clinical manifestations=====
* Hemoptysis
* Hemoptysis
* Fine rales
* Fine rales
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* High grade fever
* High grade fever


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Pleural effusion (exudative)
* Pleural effusion (exudative)
* Respiratory alkalosis  
* Respiratory alkalosis  
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* Gram positive diplococci on sputum Gram stain
* Gram positive diplococci on sputum Gram stain


==Findings suggestive of Pneumocystis carinii pneumonia==
----


===Clinical manifestations===
{{ddx|Pneumocystis carinii pneumonia}}
 
=====Clinical manifestations=====
* Immunosuppressive state
* Immunosuppressive state
* Mediastinal emphysema
* Mediastinal emphysema
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* Progressive dyspnea
* Progressive dyspnea


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Respiratory alkalosis  
* Respiratory alkalosis  
* Serum beta-D-glucan elevated
* Serum beta-D-glucan elevated
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* Interstitial infiltrate on chest radiograph
* Interstitial infiltrate on chest radiograph


==Findings suggestive of Pulmonary embolism==
----
 
{{ddx|Pulmonary embolism}}


===Clinical manifestations===
=====Clinical manifestations=====
* Calf pain / swelling  
* Calf pain / swelling  
* Decreased pulse pressure
* Decreased pulse pressure
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* Venous stasis
* Venous stasis


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Atrial fibrillation
* Atrial fibrillation
* Bone fracture
* Bone fracture
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* Right axis deviation on ECG
* Right axis deviation on ECG


==Findings suggestive of Streptococcal pneumonia==
----
 
{{ddx|Streptococcal pneumonia}}


===Clinical manifestations===
=====Clinical manifestations=====
* Pectoriloquy  
* Pectoriloquy  
* Bronchial breath sounds  
* Bronchial breath sounds  
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* Egophony  
* Egophony  


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Respiratory alkalosis  
* Respiratory alkalosis  
* Pleural effusion (exudative)  
* Pleural effusion (exudative)  
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* Lobar consolidation on chest radiograph
* Lobar consolidation on chest radiograph


==Findings suggestive of Viral pneumonia==
----
 
{{ddx|Viral pneumonia}}


===Clinical manifestations===
=====Clinical manifestations=====
* Pleuritic chest pain
* Pleuritic chest pain
* Bronchial breath sounds  
* Bronchial breath sounds  
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* Bronchovesicular breath sounds
* Bronchovesicular breath sounds


===Laboratory abnormalities===
=====Laboratory abnormalities=====
* Lymphocytosis  
* Lymphocytosis  
* Respiratory alkalosis  
* Respiratory alkalosis  
* Lobar consolidation on chest radiograph
* Lobar consolidation on chest radiograph
* Interstitial infiltrate on chest radiograph
* Interstitial infiltrate on chest radiograph

Revision as of 06:32, 9 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Instructions

Example

Differentiating Legionnaires' disease from other diseases

The following conditions must be considered in the differential diagnosis of Legionnaires' disease: DDx [1][2][3][4][5][6][7]
  • Acute interstitial pneumonia DDx
  • Mycoplasma pneumonia DDx
  • Pneumococcal pneumonia DDx
  • Pneumocystis carinii pneumonia DDx
  • Pulmonary embolism DDx
  • Streptococcal pneumonia DDx
  • Viral pneumonia DDx


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] Mahshid Mir, M.D. [3]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • High grade fever
  • Dry cough
  • Progressive dyspnea
  • Bronchial breath sounds
  • Adult respiratory distress syndrome
Laboratory abnormalities
  • Legionella urinary antigen positive
  • Alveolar consolidation on chest radiograph
  • Lobar consolidation on chest radiograph


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4] Mahshid Mir, M.D. [5]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Dry cough
  • Progressive dyspnea
  • Adult respiratory distress syndrome
Laboratory abnormalities
  • Disseminated consolidation on chest radiograph
  • Interstitial infiltrate on chest radiograph
  • Increased uptake on Gallium scan


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [6] Mahshid Mir, M.D. [7]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Dry cough
  • Pleuritic chest pain
  • Inflammed, opaque, hypomobile tympanic membrane
  • Bronchial breath sounds
Laboratory abnormalities
  • Lymphocytosis
  • Cold agglutinins positive
  • Alveolar consolidation on chest radiograph
  • Interstitial infiltrate on chest radiograph
  • Lobar consolidation on chest radiograph


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [8] Mahshid Mir, M.D. [9]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Hemoptysis
  • Fine rales
  • Pleuritic chest pain
  • Increased breath sounds
  • Bronchial breath sounds
  • Dullness on chest percussion
  • Purulent sputum
  • Shallow respiration
  • Pectoriloquy
  • Increased tactile fremitus
  • Productive cough
  • Egophony
  • High grade fever
Laboratory abnormalities
  • Pleural effusion (exudative)
  • Respiratory alkalosis
  • Parenchymal hyperlucency on chest radiograph
  • Increased uptake on Gallium scan
  • Unilateral diaphragm elevation on chest radiograph
  • Alveolar consolidation on chest radiograph
  • Lobar consolidation on chest radiograph
  • Gram positive diplococci on sputum Gram stain


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [10] Mahshid Mir, M.D. [11]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Immunosuppressive state
  • Mediastinal emphysema
  • Subcutaneous emphysema
  • Hacking cough
  • Progressive dyspnea
Laboratory abnormalities
  • Respiratory alkalosis
  • Serum beta-D-glucan elevated
  • Alveolar consolidation on chest radiograph
  • Lobar consolidation on chest radiograph
  • Interstitial infiltrate on chest radiograph


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [12] Mahshid Mir, M.D. [13]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Calf pain / swelling
  • Decreased pulse pressure
  • Dyspnea with normal chest X-ray
  • Hemoptysis
  • Hyperventilation
  • Immobility
  • Increased pulmonic component of heart sound
  • Pleuritic chest pain
  • Prior DVT
  • Pulmonary hypertension
  • Right ventricular heave
  • Right ventricular hypertrophy
  • Right-to-left shunt
  • Substernal chest pain
  • Tachypnea
  • Thrombophlebitis
  • Unilateral lower extremity edema
  • Venous stasis
Laboratory abnormalities
  • Atrial fibrillation
  • Bone fracture
  • Atelectasis on chest radiograph
  • Lobar consolidation on chest radiograph
  • Prominent pulmonary artery on chest radiograph
  • Hampton's hump on chest radiograph
  • D-dimer elevated
  • Right ventricular enlargement on echocardiography
  • Thrombus on echocardiography
  • Hypocapnia
  • Hypoxia
  • Segmental perfusion defect on lung scan
  • V/Q mismatch on lung scan
  • Pleural effusion (exudative / bloody)
  • RVH on ECG
  • Right axis deviation on ECG


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [14] Mahshid Mir, M.D. [15]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Pectoriloquy
  • Bronchial breath sounds
  • Empyema
  • Erythema nodosum
  • Purulent sputum
  • Shallow respiration
  • Increased tactile fremitus
  • Pleuritic chest pain
  • Egophony
Laboratory abnormalities
  • Respiratory alkalosis
  • Pleural effusion (exudative)
  • Increased uptake on Gallium scan
  • Gram-positive cocci in chains on sputum Gram stain
  • Alveolar consolidation on chest radiograph
  • Lobar consolidation on chest radiograph


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [16] Mahshid Mir, M.D. [17]

Differential Diagnosis
DDx Alphabetic Order
A B
C D
E F
G H
I J
K L
M N
O P
Q R
S T
U V
W X
Y Z


Template:WikiDoc Sources

Clinical manifestations
  • Pleuritic chest pain
  • Bronchial breath sounds
  • Influenza
  • Fine rales
  • Bronchovesicular breath sounds
Laboratory abnormalities
  • Lymphocytosis
  • Respiratory alkalosis
  • Lobar consolidation on chest radiograph
  • Interstitial infiltrate on chest radiograph
  1. ↑ Ferri, Fred (2011). Ferri's differential diagnosis: a practical guide to the differential diagnosis of symptoms, signs, and clinical disorders. Philadelphia, PA: Elsevier/Mosby. ISBN 978-0323076999.
  2. ↑ Siegenthaler, Walter (2007). Differential diagnosis in internal medicine: from symptom to diagnosis. Stuttgart New York: Thieme. ISBN 978-1588905512.
  3. ↑ Mesko, Dusan (2002). Differential diagnosis by laboratory medicine: a quick reference for physicians. Berlin New York: Springer-Verlag. ISBN 978-3540430575.
  4. ↑ Reeder and Felson's gamuts in radiology: comprehensive lists of roentgen differential diagnosis. Place of publication not identified: Springer. 2014. ISBN 978-1475781229.
  5. ↑ Burgener, Francis (2008). Differential diagnosis in conventional radiology. Stuttgart New York: Thieme. ISBN 978-1588902757.
  6. ↑ Gattuso, Paolo (2015). Differential diagnosis in surgical pathology. Philadelphia, PA: Saunders/Elsevier. ISBN 978-1455770137.
  7. ↑ "DXplain".
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