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==Overview==
==Overview==


'''Leptospirosis''' (also known as '''Weil's disease''', '''canicola fever''', '''canefield fever''',  '''nanukayami fever''', '''7-day fever''' and many more<ref name=NORD>[http://children.webmd.com/Weil-Syndrome Weil Syndrome<!-- Bot generated title -->]</ref>) is a [[infectious disease|bacterial]] [[zoonotic]]  disease caused by [[spirochaete]]s of the [[genus]] ''[[Leptospira]]'' that affects [[human]]s and a wide range of animals, including mammals, birds, amphibians, and reptiles. It was first described by [[Adolf Weil (physician)|Adolf Weil]] in 1886 when he reported an "acute infectious disease with [[splenomegaly|enlargement of spleen]], [[jaundice]] and [[nephritis]]". ''Leptospira'' was first observed in 1907 from a [[post mortem]] [[kidney|renal tissue]] slice.<ref>Stimson AM (1907). "Note on an organism found in yellow-fever tissue."  ''Public Health Reports'' '''22''':541.</ref>
'''Leptospirosis''' (also known as '''Weil's disease''', '''canicola fever''', '''canefield fever''',  '''nanukayami fever''', '''7-day fever''' and many more<ref name=NORD> Leptospirosis. National Organization for Rare Diseases (2015). http://rarediseases.org/rare-diseases/leptospirosis/ Accessed on July 28, 2016 </ref>) is a [[infectious disease|bacterial]] [[zoonotic]]  disease caused by [[spirochaete]]s of the [[genus]] ''[[Leptospira]]'' that affects [[human]]s and a wide range of animals, including mammals, birds, amphibians, and reptiles.<ref name=Leptospirosis> Leptospirosis. Centers for Disease Control and Prevention (2015). https://www.cdc.gov/leptospirosis/ Accessed on July 28, 2016 </ref> It was first described by [[Adolf Weil (physician)|Adolf Weil]] in 1886 when he reported an "acute infectious disease with [[splenomegaly|enlargement of spleen]], [[jaundice]] and [[nephritis]]". ''Leptospira'' was first observed in 1907 from a [[post mortem]] [[kidney|renal tissue]] slice.<ref>Stimson AM (1907). "Note on an organism found in yellow-fever tissue."  ''Public Health Reports'' '''22''':541.</ref>


Though being recognised among the world's most common [[zoonosis|zoonoses]], leptospirosis is a relatively rare  bacterial [[infection]] in humans. The infection is commonly transmitted to humans by allowing [[fresh water]] that has been contaminated by animal [[urine]] to come in contact with unhealed breaks in the [[skin]], [[eye]]s  or with the [[mucous membrane]]s. Outside of [[Tropics|tropical]] areas, leptospirosis cases have a relatively distinct seasonality with most of them occurring August-September/February-March.
Though being recognised among the world's most common [[zoonosis|zoonoses]], leptospirosis is a relatively rare  bacterial [[infection]] in humans. The infection is commonly transmitted to humans by allowing [[fresh water]] that has been contaminated by animal [[urine]] to come in contact with unhealed breaks in the [[skin]], [[eye]]s  or with the [[mucous membrane]]s. Outside of [[Tropics|tropical]] areas, leptospirosis cases have a relatively distinct seasonality with most of them occurring August-September/February-March.

Revision as of 14:51, 28 July 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Leptospirosis (also known as Weil's disease, canicola fever, canefield fever, nanukayami fever, 7-day fever and many more[1]) is a bacterial zoonotic disease caused by spirochaetes of the genus Leptospira that affects humans and a wide range of animals, including mammals, birds, amphibians, and reptiles.[2] It was first described by Adolf Weil in 1886 when he reported an "acute infectious disease with enlargement of spleen, jaundice and nephritis". Leptospira was first observed in 1907 from a post mortem renal tissue slice.[3]

Though being recognised among the world's most common zoonoses, leptospirosis is a relatively rare bacterial infection in humans. The infection is commonly transmitted to humans by allowing fresh water that has been contaminated by animal urine to come in contact with unhealed breaks in the skin, eyes or with the mucous membranes. Outside of tropical areas, leptospirosis cases have a relatively distinct seasonality with most of them occurring August-September/February-March.

References

  1. Leptospirosis. National Organization for Rare Diseases (2015). http://rarediseases.org/rare-diseases/leptospirosis/ Accessed on July 28, 2016
  2. Leptospirosis. Centers for Disease Control and Prevention (2015). https://www.cdc.gov/leptospirosis/ Accessed on July 28, 2016
  3. Stimson AM (1907). "Note on an organism found in yellow-fever tissue." Public Health Reports 22:541.