Ancylostomiasis: Difference between revisions

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convincing people to maintaining them in a clean, functional state, thereby making
convincing people to maintaining them in a clean, functional state, thereby making
them conducive to use.  
them conducive to use.  
==Treatment==
The drug of choice for the treatment of hookworm disease is [[mebendazole]] which
is effective against both species, and in addition, will remove the intestinal
worm Ascaris also, if present. The drug is very efficient, requiring only a
single dose and is inexpensive, the perfect drug. However, treatment requires
more than giving the anthelmintic, the patient should also receive dietary
supplements to improve their general level of health, in particular iron
supplementation is very important. Iron is an important constituent of a
multitude of enzyme systems involved in energy metabolism, DNA synthesis and
drug detoxification.
An infection of ''N. americanus'' parasites can be treated by using [[Imidazole|benzimidazoles]], [[albendazole]], and [[mebendazole]]. A blood transfusion may be necessary in severe cases of anemia. Light infections are usually left untreated in areas where reinfection is common. Iron supplements and a diet high in protein will speed the recovery process.<ref>"hookworm disease." Encyclopædia Britannica. 2009. Encyclopædia Britannica Online. 06 Dec. 2009 <http://www.britannica.com/EBchecked/topic/271350/hookworm-disease>.</ref>  In a case study involving 56-60 men with ''[[Trichuris trichiura]]'' and/or ''N. americanus'' infections, both albendazole and mebendazole were 90% effective in curing ''T. trichiura''.  However, albendazole had a 95% cure rate for ''N. americanus'', while mebendazole only had a 21% cure rate.  This suggests albendazole is most effective for treating both ''T. trichiura'' and ''N. americanus''.<ref> Holzer, B. R.; and Frey, F. J. (February 1987). "Differential efficacy of mebendazole and albendazole against Necator americanus but not for Trichuris trichiura infestations". European Journal of Clinical Pharmacology. 32 (6): 635-637. http://www.springerlink.com/content/k000065915k70257/</ref>


==Gallery==
==Gallery==

Revision as of 19:00, 11 August 2015


Ancylostomiasis
ICD-10 K29.0-K29.7
ICD-9 535.0-535.5
DiseasesDB 34500

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Classification

Pathophysiology

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Differentiating Ancylostomiasis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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Prevention

Control of this parasite should be directed against reducing the level of environmental contamination. Treatment of heavily infected individuals is one way to reduce the source of contamination (one study has estimated that 60% of the total worm burden resides in less than 10% of the population). Other obvious methods are to improve access to sanitation, e.g. toilets, but also convincing people to maintaining them in a clean, functional state, thereby making them conducive to use.

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References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 "Public Health Image Library (PHIL)".

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