Onychomycosis laboratory findings: Difference between revisions
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==Laboratory findings== | |||
If all nails are affected then fungal infection is improbable. To avoid misdiagnosis as [[psoriasis]], [[lichen planus]], [[contact dermatitis]], [[Physical trauma|trauma]], nail bed [[tumor]] or [[yellow nail syndrome]], laboratory confirmation may be necessary. The three main approaches are potassium hydroxide smear, culture and histology. This involves microscopic examination and culture of nail scrapings or clippings. Recent results indicate that the most sensitive diagnostic approaches are direct smear combined with histological examination<ref>PMID 17222296</ref> and nail plate biopsy using periodic acid-Schiff stain<ref>PMID 12894064</ref>. | |||
==References== | ==References== |
Revision as of 20:06, 11 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Laboratory findings
If all nails are affected then fungal infection is improbable. To avoid misdiagnosis as psoriasis, lichen planus, contact dermatitis, trauma, nail bed tumor or yellow nail syndrome, laboratory confirmation may be necessary. The three main approaches are potassium hydroxide smear, culture and histology. This involves microscopic examination and culture of nail scrapings or clippings. Recent results indicate that the most sensitive diagnostic approaches are direct smear combined with histological examination[1] and nail plate biopsy using periodic acid-Schiff stain[2].