Brain tumor causes: Difference between revisions
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{{Brain tumor}} | {{Brain tumor}} | ||
==Cause== | |||
Epidemiological studies are required to determine risk factors.<ref>{{cite journal|last1=Krishnatreya|first1=M|last2=Kataki|first2=AC|last3=Sharma|first3=JD|last4=Bhattacharyya|first4=M|last5=Nandy|first5=P|last6=Hazarika|first6=M|title=Brief descriptive epidemiology of primary malignant brain tumors from North-East India.|journal=Asian Pacific journal of cancer prevention : APJCP|date=2014|volume=15|issue=22|pages=9871–3|pmid=25520120|doi=10.7314/apjcp.2014.15.22.9871}}</ref> Aside from exposure to [[vinyl chloride]] or [[ionizing radiation]], there are no known environmental factors associated with brain tumors. Mutations and deletions of so-called [[tumor suppressor gene]]s, such as [[P53]], are thought to be the cause of some forms of brain tumor.<ref>{{cite book | author = Kleihues P, Ohgaki H, Eibl RH, Reichel MB, Mariani L, Gehring M, Petersen I, Höll T, von Deimling A, Wiestler OD, Schwab M | chapter = Type and frequency of p53 mutations in tumors of the nervous system and its coverings | title = Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors | pages = 25–31 | year = 1994 | publisher = Springer |isbn=3540573518 |series=Recent results in cancer research |volume=135}}</ref> Inherited conditions, such as [[Von Hippel–Lindau disease]], [[multiple endocrine neoplasia]], and [[Neurofibromatosis|neurofibromatosis type 2]] carry a high risk for the development of brain tumors. | |||
Although studies have not shown any link between [[Mobile phone radiation and health|cell phone or mobile phone radiation]] and the occurrence of brain tumors,<ref>{{cite journal | author = Frei P, Poulsen AH, Johansen C, Olsen JH, Steding-Jessen M, Schüz J | title = Use of mobile phones and risk of brain tumours: update of Danish cohort study. | journal = BMJ (Clinical research ed.) | volume = 343 | pages = d6387 | date = 19 October 2011 | pmid = 22016439 | pmc = 3197791 | doi = 10.1136/bmj.d6387 }}</ref> the [[World Health Organization]] has classified mobile phone radiation on the [[International Agency for Research on Cancer|IARC]] scale into [[List of IARC Group 2B carcinogens|Group 2B]] – possibly carcinogenic.<ref name="WHO_IARC_110531">{{cite press release|url= http://www.iarc.fr/en/media-centre/pr/2011/pdfs/pr208_E.pdf |format= PDF|title= IARC classifies radiofrequency electromagnetic fields as possibly carcinogenic to humans|work= [[World Health Organization]] press release N° 208|publisher= [[International Agency for Research on Cancer]]|date= 31 May 2011|accessdate= 2 June 2011}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 18:21, 19 August 2015
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Brain tumor Microchapters |
Cause
Epidemiological studies are required to determine risk factors.[1] Aside from exposure to vinyl chloride or ionizing radiation, there are no known environmental factors associated with brain tumors. Mutations and deletions of so-called tumor suppressor genes, such as P53, are thought to be the cause of some forms of brain tumor.[2] Inherited conditions, such as Von Hippel–Lindau disease, multiple endocrine neoplasia, and neurofibromatosis type 2 carry a high risk for the development of brain tumors.
Although studies have not shown any link between cell phone or mobile phone radiation and the occurrence of brain tumors,[3] the World Health Organization has classified mobile phone radiation on the IARC scale into Group 2B – possibly carcinogenic.[4]
References
- ↑ Krishnatreya, M; Kataki, AC; Sharma, JD; Bhattacharyya, M; Nandy, P; Hazarika, M (2014). "Brief descriptive epidemiology of primary malignant brain tumors from North-East India". Asian Pacific journal of cancer prevention : APJCP. 15 (22): 9871–3. doi:10.7314/apjcp.2014.15.22.9871. PMID 25520120.
- ↑ Kleihues P, Ohgaki H, Eibl RH, Reichel MB, Mariani L, Gehring M, Petersen I, Höll T, von Deimling A, Wiestler OD, Schwab M (1994). "Type and frequency of p53 mutations in tumors of the nervous system and its coverings". Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors. Recent results in cancer research. 135. Springer. pp. 25–31. ISBN 3540573518.
- ↑ Frei P, Poulsen AH, Johansen C, Olsen JH, Steding-Jessen M, Schüz J (19 October 2011). "Use of mobile phones and risk of brain tumours: update of Danish cohort study". BMJ (Clinical research ed.). 343: d6387. doi:10.1136/bmj.d6387. PMC 3197791. PMID 22016439.
- ↑ "IARC classifies radiofrequency electromagnetic fields as possibly carcinogenic to humans" (PDF). World Health Organization press release N° 208 (Press release). International Agency for Research on Cancer. 31 May 2011. Retrieved 2 June 2011.