Merkel cell cancer classification: Difference between revisions

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* Intermediate: solid pattern (most common).
* Intermediate: solid pattern (most common).
* Small cell: diffuse, few high density granules on ultrasound examination (second most common).
* Small cell: diffuse, few high density granules on ultrasound examination (second most common).
 
==Staging==
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Stage'''
| align="center" style="background:#f0f0f0;"|'''Primary Tumor'''
| align="center" style="background:#f0f0f0;"|'''Lymph Node'''
| align="center" style="background:#f0f0f0;"|'''Metastasis'''
|-
| 0||In situ primary tumor||No regional lymph node metastasis||No distant metastasis
|-
| IA||Less than or equal to 2 cm maximum tumor dimension||Nodes negative by pathologic exam||No distant metastasis
|-
| IB||Less than or equal to 2 cm maximum tumor dimension||Nodes negative by clinical exam* (no pathologic node exam performed)||No distant metastasis
|-
| IIA||Greater than 2 cm tumor dimension||Nodes negative by pathologic exam||No distant metastasis
|-
| IIB||Greater than 2 cm tumor dimension||Nodes negative by clinical exam* (no pathologic node exam performed)||No distant metastasis
|-
| IIC||Primary tumor invades bone, muscle, fascia, or cartilage||No regional lymph node metastasis||No distant metastasis
|-
|  IIIA||Any size tumor (includes invading tumors)||Micrometastasis**||No distant metastasis
|-
|  IIIB||Any size tumor (includes invading tumors)||"Macrometastasis*** -OR- In transit metastasis****"||No distant metastasis
|-
|  IV||Any size tumor (includes invading tumors)||Any lymph node metastasis||Metastasis beyond regional lymph nodes
|}
==References==
==References==



Revision as of 13:08, 20 August 2015

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Classification

Histologically, MCC has been classified into three distinct subtypes:

  • Trabecular: classic pattern, large-cell type, high density or granules on ultrasound examination.
  • Intermediate: solid pattern (most common).
  • Small cell: diffuse, few high density granules on ultrasound examination (second most common).

Staging

Stage Primary Tumor Lymph Node Metastasis
0 In situ primary tumor No regional lymph node metastasis No distant metastasis
IA Less than or equal to 2 cm maximum tumor dimension Nodes negative by pathologic exam No distant metastasis
IB Less than or equal to 2 cm maximum tumor dimension Nodes negative by clinical exam* (no pathologic node exam performed) No distant metastasis
IIA Greater than 2 cm tumor dimension Nodes negative by pathologic exam No distant metastasis
IIB Greater than 2 cm tumor dimension Nodes negative by clinical exam* (no pathologic node exam performed) No distant metastasis
IIC Primary tumor invades bone, muscle, fascia, or cartilage No regional lymph node metastasis No distant metastasis
IIIA Any size tumor (includes invading tumors) Micrometastasis** No distant metastasis
IIIB Any size tumor (includes invading tumors) "Macrometastasis*** -OR- In transit metastasis****" No distant metastasis
IV Any size tumor (includes invading tumors) Any lymph node metastasis Metastasis beyond regional lymph nodes

References