Merkel cell cancer other diagnostic studies: Difference between revisions
Jump to navigation
Jump to search
YazanDaaboul (talk | contribs) |
No edit summary |
||
| Line 10: | Line 10: | ||
*On biopsy, Merkel cell cancer is characterized by positive staining on [[Keratin 20|cytokeratin-20]] immunohistochemical assay.<ref name="pmid18280333">{{cite journal| author=Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF et al.| title=Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. | journal=J Am Acad Dermatol | year= 2008 | volume= 58 | issue= 3 | pages= 375-81 | pmid=18280333 | doi=10.1016/j.jaad.2007.11.020 | pmc=PMC2335370 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18280333 }} </ref> | *On biopsy, Merkel cell cancer is characterized by positive staining on [[Keratin 20|cytokeratin-20]] immunohistochemical assay.<ref name="pmid18280333">{{cite journal| author=Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF et al.| title=Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. | journal=J Am Acad Dermatol | year= 2008 | volume= 58 | issue= 3 | pages= 375-81 | pmid=18280333 | doi=10.1016/j.jaad.2007.11.020 | pmc=PMC2335370 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18280333 }} </ref> | ||
*On electron microscopy, Merkel cell cancer is characterized by the presence of neurosecretory granules within cytoplasmic extensions.<ref name="pmid18280333">{{cite journal| author=Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF et al.| title=Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. | journal=J Am Acad Dermatol | year= 2008 | volume= 58 | issue= 3 | pages= 375-81 | pmid=18280333 | doi=10.1016/j.jaad.2007.11.020 | pmc=PMC2335370 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18280333 }} </ref> | *On electron microscopy, Merkel cell cancer is characterized by the presence of neurosecretory granules within cytoplasmic extensions.<ref name="pmid18280333">{{cite journal| author=Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF et al.| title=Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. | journal=J Am Acad Dermatol | year= 2008 | volume= 58 | issue= 3 | pages= 375-81 | pmid=18280333 | doi=10.1016/j.jaad.2007.11.020 | pmc=PMC2335370 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18280333 }} </ref> | ||
*Sentinel lymph node biopsy is used to check for cancer cells.<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdp</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:50, 20 August 2015
|
Merkel cell cancer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Merkel cell cancer other diagnostic studies On the Web |
|
American Roentgen Ray Society Images of Merkel cell cancer other diagnostic studies |
|
Risk calculators and risk factors for Merkel cell cancer other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
On biopsy, Merkel cell cancer is characterized by the presence of neurosecretory granules within cytoplasmic extensions and positivity on cytokeratin-20 immunohistochemical staining.
Biopsy
- Skin biopsy is required for the diagnosis of Merkel cell cancer.
- The histopathological diagnosis of Merkel cell tumor is difficult, and the majority of cases with Merkel cell cancer are often misdiagnosed.
- Cytokeratin-20 immunohistochemical staining is required for the histopathological diagnosis of Merkel cell cancer.
- On biopsy, Merkel cell cancer is characterized by positive staining on cytokeratin-20 immunohistochemical assay.[1]
- On electron microscopy, Merkel cell cancer is characterized by the presence of neurosecretory granules within cytoplasmic extensions.[1]
- Sentinel lymph node biopsy is used to check for cancer cells.[2]
References
- ↑ 1.0 1.1 Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF; et al. (2008). "Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features". J Am Acad Dermatol. 58 (3): 375–81. doi:10.1016/j.jaad.2007.11.020. PMC 2335370. PMID 18280333.
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdp