Ependymoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

WHO classifies Ependymoma into three grades based on pleomorphism, mitotic count, cellularity, vascular proliferation, invasion.

Classification

WHO Grade I

• Myxopapillary Ependymomas
• Subependymomas

WHO Grade II

• Cellular Ependymoma
• Papillary Ependymoma
• Clear cell Ependymoma

Grade III

• Anaplastic Ependymoma
• Features include
  • Increased cellularity and increased mitotic activity
  • Microvascular proliferation
  • Necrosis

References

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