Extramammary Paget's disease other diagnostic studies: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Extramammary Paget's disease}} | {{Extramammary Paget's disease}} | ||
{{CMG}} | {{CMG}}{{AE}}{{Simrat}} | ||
==Overview== | ==Overview== | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Because EMPD extends beyond the visibly involved margins, obviously involved skin should be examined by using transverse frozen sections or serial vertical sections. Perform skin biopsy to evaluate possible EMPD in patients in whom ongoing therapy is ineffective. See the image below. | |||
Skin biopsy of the lesion is performed to get an accurate diagnosis of extramammary Paget disease as there are several other genital skin diseases that may appear similar. Under microscopy, the presence of Paget cells along with other histological findings confirms diagnosis. Special stains may be necessary to distinguish Paget disease from early melanoma (melanoma in situ). See extramammary Paget disease pathology. | |||
The diagnosis of extramammary Paget disease (EMPD) requires a high degree of clinical suspicion followed by skin biopsy with pathologic correlation. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 04:19, 3 February 2016
Extramammary Paget's disease Microchapters |
Differentiating Extramammary Paget's disease from other Diseases |
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Directions to Hospitals Treating Extramammary Paget's disease |
Risk calculators and risk factors for Extramammary Paget's disease other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Other Diagnostic Studies
Because EMPD extends beyond the visibly involved margins, obviously involved skin should be examined by using transverse frozen sections or serial vertical sections. Perform skin biopsy to evaluate possible EMPD in patients in whom ongoing therapy is ineffective. See the image below.
Skin biopsy of the lesion is performed to get an accurate diagnosis of extramammary Paget disease as there are several other genital skin diseases that may appear similar. Under microscopy, the presence of Paget cells along with other histological findings confirms diagnosis. Special stains may be necessary to distinguish Paget disease from early melanoma (melanoma in situ). See extramammary Paget disease pathology. The diagnosis of extramammary Paget disease (EMPD) requires a high degree of clinical suspicion followed by skin biopsy with pathologic correlation.