Ganglioneuroma overview: Difference between revisions
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'''Ganglioneuroma''' is a [[tumor]] in the nerve cells of the [[peripheral nervous system]].<ref name="MedlinePlus">{{cite web | '''Ganglioneuroma''' is a [[tumor]] in the nerve cells of the [[peripheral nervous system]].<ref name="MedlinePlus">{{cite web | ||
| url = http://www.nlm.nih.gov/medlineplus/ency/article/001437.htm | | url = http://www.nlm.nih.gov/medlineplus/ency/article/001437.htm | ||
==Classification== | |||
==Pathophysiology== | |||
Ganglioglioma arises from neuronal glial cells, which are cells of the [[central nervous system]]. It is a rare disease that tends to affect children, adolescents, and young adults. Ganglioglioma affects male and female equally. On gross pathology, ganglioglioma varies from partially cystic mass with a mural nodule to a solid mass expanding the overlying [[gyrus]]. On microscopic pathology, ganglioglioma is composed of [[ganglion cells]] and neoplastic glial cells with positive staining for [[synaptophysin]], neuronal specific enolase, and [[GFAP]]. | |||
==Causes== | |||
There are no established causes for ganglioglioma. | |||
==Differentiating brain tumors from other diseases== | |||
Ganglioglioma must be differentiated from dysembryoplastic neuroepithelial tumors, pleomorphic xanthoastrocytoma, [[oligodendroglioma]], desmoplastic infantile ganglioglioma, [[astrocytoma]], [[ependymoma]], and [[transverse myelitis]]. | |||
==Epidemiology and Demographics== | |||
Ganglioglioma is the most frequent neuronal-glial [[CNS]] neoplasm. It is a rare disease that tends to affect children, adolescents, and young adults. Ganglioglioma affects male and female equally. | |||
==Risk factors== | |||
There are no established risk factors for ganglioglioma. | |||
==Natural History, Complications and Prognosis== | |||
If left untreated, patients with ganglioglioma may progress to develop local recurrence. Complications that can develop as a result of ganglioglioma are [[metastasis]] and local recurrence. Prognosis is generally good with treatment.<ref name=dd>Features of ganglioglioma. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/ganglioglioma</ref> | |||
| title = Ganglioneuroma | | title = Ganglioneuroma | ||
Revision as of 13:52, 11 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ganglioneuroma is a tumor in the nerve cells of the peripheral nervous system.
| title = Ganglioneuroma
| first = Kenneth
| last = Gross
| date = 2006-09-25
| accessdate = 2007-05-09
}}</ref> It can be found also in the eye (retina), or in the cortex of adrenal glands.