Craniopharyngioma medical therapy: Difference between revisions
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The mainstay of therapy for craniopharyngioma is surgery with or without radiation. Although systemic therapy is generally not utilized, a small series has shown that the use of '''subcutaneous pegylated [[interferon]] alpha-2b''' to manage ''cystic recurrences'' can result in durable responses.<ref>Rx of Craniopharyngioma. Cancer gov. http://www.cancer.gov/types/brain/hp/child-cranio-treatment-pdq#link/_40_toc</ref> | The mainstay of therapy for craniopharyngioma is surgery with or without radiation. Although systemic therapy is generally not utilized, a small series has shown that the use of '''subcutaneous pegylated [[interferon]] alpha-2b''' to manage ''cystic recurrences'' can result in durable responses.<ref>Rx of Craniopharyngioma. Cancer gov. http://www.cancer.gov/types/brain/hp/child-cranio-treatment-pdq#link/_40_toc</ref> | ||
The chemotherapy drugs [[Paclitaxel]] and [[Carboplatin]] have shown a clinical (but not statistical) significance in increasing the survival rate in patients who've had gross total resections of their malignant | The chemotherapy drugs [[Paclitaxel]] and [[Carboplatin]] have shown a clinical (but not statistical) significance in increasing the survival rate in patients who've had gross total resections of their malignant tumors. | ||
Intracavitary instillation of radioactive P-32, bleomycin, or interferon-alpha, for those with ''cystic recurrences''. | |||
==References== | ==References== | ||
Revision as of 18:41, 23 August 2015
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Craniopharyngioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Craniopharyngioma medical therapy On the Web |
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American Roentgen Ray Society Images of Craniopharyngioma medical therapy |
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Risk calculators and risk factors for Craniopharyngioma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with craniopharyngioma have many treatment options. The selection depends on the size, location of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods.
Medical Therapy
The mainstay of therapy for craniopharyngioma is surgery with or without radiation. Although systemic therapy is generally not utilized, a small series has shown that the use of subcutaneous pegylated interferon alpha-2b to manage cystic recurrences can result in durable responses.[1]
The chemotherapy drugs Paclitaxel and Carboplatin have shown a clinical (but not statistical) significance in increasing the survival rate in patients who've had gross total resections of their malignant tumors.
Intracavitary instillation of radioactive P-32, bleomycin, or interferon-alpha, for those with cystic recurrences.
References
- ↑ Rx of Craniopharyngioma. Cancer gov. http://www.cancer.gov/types/brain/hp/child-cranio-treatment-pdq#link/_40_toc