Diffuse large B cell lymphoma laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory tests helpful in the diagnosis of diffuse large B cell lymphoma include complete blood count, LDH and lymph node biopsy | Laboratory tests helpful in the diagnosis of diffuse large B cell lymphoma include complete blood count, LDH, and lymph node biopsy | ||
==Laboratory Tests== | ==Laboratory Tests== | ||
Laboratory studies include<ref>{{cite web | title = Non-Hodgkin's Lymphomas (NCCN.org) | url = http://www.nccn.org/professionals/physician_gls/PDF/nhl.pdf }}</ref> | Laboratory studies include<ref>{{cite web | title = Non-Hodgkin's Lymphomas (NCCN.org) | url = http://www.nccn.org/professionals/physician_gls/PDF/nhl.pdf }}</ref> | ||
* [[Complete | * [[Complete blood count]] | ||
* | * Serum lactate dehydrogenase (LDH) | ||
* [[Comprehensive metabolic panel]] | * [[Comprehensive metabolic panel]] | ||
* Lymph node or extranodal tissue biopsy | * Lymph node or extranodal tissue biopsy | ||
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* [[MUGA scan]] or [[echocardiograms]] are recommended when anthracyclines and anthracenedione containing regimens are used | * [[MUGA scan]] or [[echocardiograms]] are recommended when anthracyclines and anthracenedione containing regimens are used | ||
* [[Bone marrow biopsy]] with or without aspirate is essential in all cases where treatment is considered; however, there are circumstances where it may be deferred | * [[Bone marrow biopsy]] with or without aspirate is essential in all cases where treatment is considered; however, there are circumstances where it may be deferred | ||
* | * Hepatitis B testing prior to initiation of treatment in all patients who will receive anti CD20 monoclonal antibody-based regimens and anyone with a risk factor | ||
* | * Hepatitis C testing is needed in high-risk patients | ||
==References== | ==References== | ||
Revision as of 13:38, 25 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory tests helpful in the diagnosis of diffuse large B cell lymphoma include complete blood count, LDH, and lymph node biopsy
Laboratory Tests
Laboratory studies include[1]
- Complete blood count
- Serum lactate dehydrogenase (LDH)
- Comprehensive metabolic panel
- Lymph node or extranodal tissue biopsy
- CT chest/abdominal/pelvic with oral and intravenous contrast (unless co-existent renal insufficiency)
- MUGA scan or echocardiograms are recommended when anthracyclines and anthracenedione containing regimens are used
- Bone marrow biopsy with or without aspirate is essential in all cases where treatment is considered; however, there are circumstances where it may be deferred
- Hepatitis B testing prior to initiation of treatment in all patients who will receive anti CD20 monoclonal antibody-based regimens and anyone with a risk factor
- Hepatitis C testing is needed in high-risk patients