Mucinous cystadenocarcinoma differential diagnosis: Difference between revisions
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{{Mucinous cystadenocarcinoma}} | {{Mucinous cystadenocarcinoma}} | ||
{{CMG}}; {{AE}} {{Ammu}} | |||
==Overview== | |||
==Pathogenesis== | |||
==Genetics== | |||
==Associated Conditions== | |||
==Gross Pathology== | |||
Features: | |||
Multiloculated. | |||
Sticky, gelatinous fluid (glycoprotein). | |||
+/-Necrosis. | |||
Typically unilateral.[3] | |||
==Microscopic Pathology== | |||
Features: | |||
Mucinous differentiation. | |||
Tall columnar cells in glands with apical mucin. | |||
May have an endocervical-like or intestinal-like appearance - see subtypes. | |||
Invasive morphology - one of the following: | |||
Back-to-back glands/confluent growth pattern. | |||
Desmoplastic stromal response. | |||
Cribriforming of glands. | |||
Malignant characteristics: | |||
+/-Nuclear atypia. | |||
+/-Necrosis. | |||
No cilia. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 20:58, 23 February 2016
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Differentiating Mucinous Cystadenocarcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Pathogenesis
Genetics
Associated Conditions
Gross Pathology
Features:
Multiloculated. Sticky, gelatinous fluid (glycoprotein). +/-Necrosis. Typically unilateral.[3]
Microscopic Pathology
Features:
Mucinous differentiation. Tall columnar cells in glands with apical mucin. May have an endocervical-like or intestinal-like appearance - see subtypes. Invasive morphology - one of the following: Back-to-back glands/confluent growth pattern. Desmoplastic stromal response. Cribriforming of glands. Malignant characteristics: +/-Nuclear atypia. +/-Necrosis. No cilia.