Acute lymphoblastic leukemia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]

Overview

Common physical examination findings of acute lymphoblastic leukemia include lymphadenopathy, hepatomegaly, stridor, splenomegaly,pallor, petechiae, bruising, papilledema, nuchar rigidity, craneal nerve palsy and in males testicular enlargement.

Physical Examination

Neck

• Lymphadenopathy

Pulmonary

• Stridor due mediastinal mass

Abdomen

• Hepatomegaly
• Splenomegaly

Skin

• Pallor (anemia)
• Petechiae
• Bruising

CNS

• Papilledema
• Nuchar rigidity
• Craneal nerve palsy

Genitourinary

• Males: Testicular enlargement