Paraganglioma other diagnostic studies: Difference between revisions
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{{CMG}} {{AE}} {{AAM}} | {{CMG}} {{AE}} {{AAM}} | ||
==Overview== | ==Overview== | ||
[[Immunohistochemistry]] and [[ | [[Immunohistochemistry]] and [[histochemistry]] are used in the diagnosis of paraganglioma. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
*'''[[Immunohistochemistry]]''' | *'''[[Immunohistochemistry]]''' | ||
The chief cells located in the cell balls are positive for [[chromogranin]], [[synaptophysin]], neuron specific enolase, [[serotonin]] and [[neurofilament]]; they are [[S-100 protein]] negative. | :The chief cells located in the cell balls are positive for [[chromogranin]], [[synaptophysin]], neuron specific enolase, [[serotonin]] and [[neurofilament]]; they are [[S-100 protein]] negative. | ||
*'''[[Histochemistry]]''' | *'''[[Histochemistry]]''' | ||
The paraganglioma cells are argyrophilic, [[periodic acid Schiff]] negative, [[mucicarmine]] negative, and [[argentaffin]] negative. | :The paraganglioma cells are argyrophilic, [[periodic acid Schiff]] negative, [[mucicarmine]] negative, and [[argentaffin]] negative. | ||
==References== | ==References== |
Revision as of 14:33, 31 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Immunohistochemistry and histochemistry are used in the diagnosis of paraganglioma.
Other Diagnostic Studies
- The chief cells located in the cell balls are positive for chromogranin, synaptophysin, neuron specific enolase, serotonin and neurofilament; they are S-100 protein negative.
- The paraganglioma cells are argyrophilic, periodic acid Schiff negative, mucicarmine negative, and argentaffin negative.