Wilms' tumor causes: Difference between revisions
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==Overview== | ==Overview== | ||
Wilms' tumor may be caused | Wilms' tumor may be caused by either genetic mutations or chromosomal alterations. | ||
==Causes== | ==Causes== | ||
* Genetic mutations: <ref name="cancergov"> National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq </ref> | * Genetic mutations: <ref name="cancergov"> National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq </ref> |
Revision as of 15:28, 1 September 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Wilms' tumor Microchapters |
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Wilms' tumor causes On the Web |
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Overview
Wilms' tumor may be caused by either genetic mutations or chromosomal alterations.
Causes
- Genetic mutations: [1]
- Wilms tumor 1 gene (WT1)
- WT2
- WTX
- Other genes and chromosomal alterations:
- 1q
- 16q and 1p
- CACNA1E
- 7p21
- SKCG-1
- TP53 (tumor suppressor gene)
- FBXW7
- PTCH1
- DICER1
- MYCN
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq