Pheochromocytoma natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
Prognosis of pheochromocytoma is generally good but metastatic pheochromocytoma has a 5 year survival rate of approximately 45%.<ref name="cancergov"> National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc</ref> Massive release of [[catecholamines]] can causes damage to myocytes. | Prognosis of pheochromocytoma is generally good but metastatic pheochromocytoma has a 5 year survival rate of approximately 45%.<ref name="cancergov"> National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc</ref> Massive release of [[catecholamines]] can causes damage to myocytes. | ||
==Complication== | ==Natural History, Complication and Prognosis== | ||
===Complication=== | |||
The massive release of [[catecholamines]] in pheochromocytoma can cause damage to myocytes.<ref name=Goldman_327>{{Harvnb|Goldman|2011|pp=327}}</ref> This damage may be due to either compromising the [[coronary microcirculation]] or by direct toxic effects on the myocytes.<ref name=Goldman_327 /> | The massive release of [[catecholamines]] in pheochromocytoma can cause damage to myocytes.<ref name=Goldman_327>{{Harvnb|Goldman|2011|pp=327}}</ref> This damage may be due to either compromising the [[coronary microcirculation]] or by direct toxic effects on the myocytes.<ref name=Goldman_327 /> | ||
Other complication may include: | Other complication may include: | ||
Revision as of 20:49, 2 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Prognosis of pheochromocytoma is generally good but metastatic pheochromocytoma has a 5 year survival rate of approximately 45%.[1] Massive release of catecholamines can causes damage to myocytes.
Natural History, Complication and Prognosis
Complication
The massive release of catecholamines in pheochromocytoma can cause damage to myocytes.[2] This damage may be due to either compromising the coronary microcirculation or by direct toxic effects on the myocytes.[2] Other complication may include:
Prognosis
The 5-year survival in the setting of metastatic disease (whether identified at the time of initial diagnosis or identified postoperatively as recurrent disease) is 40% to 45%
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc
- ↑ 2.0 2.1 Goldman 2011, pp. 327