Gastrointestinal stromal tumor differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Gastrointestinal stromal tumor Microchapters
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Overview

Gastrointestinal stromal tumor must be differentiated from gastrointestinal leiomyoma, gastrointestinal leiomyosarcoma, gastrointestinal lymphoma / gastric lymphoma, gastrointestinal schwannoma and gastrointestinal carcinoid.

Differential Diagnosis

General imaging differential considerations include:

• Gastrointestinal leiomyoma:

• Most common in the oesophagus, accounting for 75% of mesenchymal tumours 1
• Rare in the remainder of the gastrointestinal tract

• Gastrointestinal leiomyosarcoma: rare
• Gastrointestinal lymphoma / gastric lymphoma:

• More extensive mural thickening
• Aeurysmal dilatation common

• Gastrointestinal schwannoma
• Gastrointestinal carcinoid