Adrenolipoma pathophysiology: Difference between revisions
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Macroscopic examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> | Macroscopic examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> | ||
Central congested, red to brown lesion with thin cortical rim | Central congested, red to brown lesion with thin cortical rim, large lesions may contain [[haemorrhage]] or [[infarction]] | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
Histological examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> | Histological examination demonstrates:<ref name="radiopaedia"> http://radiopaedia.org/articles/adrenal-myelolipoma </ref> |
Revision as of 15:43, 8 September 2015
Adrenolipoma Microchapters |
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Adrenolipoma pathophysiology On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Pathogenesis
The most widely accepted theory in pathogenesis of adrenolipoma is the existence of metaplasia of the reticuloendothelial cells of blood capillaries in the adrenal gland in response to stimuli such as necrosis, infection, or stress.
Gross Pathology
Macroscopic examination demonstrates:[1]
Central congested, red to brown lesion with thin cortical rim, large lesions may contain haemorrhage or infarction
Microscopic Pathology
Histological examination demonstrates:[1]
- Variable amounts of mature adipocytes (with distended lipid vacuoles) similar to bone marrow
- Variable amounts of hematopoietic cells (including cells from myeloid, erythroid and megakaryocytic cells lines)