Multiple myeloma physical examination: Difference between revisions
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==Overview== | ==Overview== | ||
Patients with multiple usually appear fatigued and lethargic. Physical examination of patients with multiple myeloma is usually remarkable for [[pallor]], [[purpura]], [[hepatosplenomegaly]], [[carpal tunnel syndrome]], and signs of [[cord compression]]. Multiple myeloma affects not only the bone marrow, but also spreads to other organ systems. This therefore, requires a detailed assessment of various organ systems. Any of these physical findings may warrant further evaluation, and thus leads to an incidental diagnosis of multiple myeloma. | Patients with multiple usually appear fatigued and lethargic.<ref>Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma#Signs_and_symptoms Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/signs-and-symptoms/?region=mb Accessed on September 20th 2015</ref> Physical examination of patients with multiple myeloma is usually remarkable for [[pallor]], [[purpura]], [[hepatosplenomegaly]], [[carpal tunnel syndrome]], and signs of [[cord compression]].<ref>Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma#Signs_and_symptoms Accessed on September, 20th 2015</ref><ref>Multiple myeloma. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/signs-and-symptoms/?region=mb Accessed on September 20th 2015</ref> Multiple myeloma affects not only the bone marrow, but also spreads to other organ systems. This therefore, requires a detailed assessment of various organ systems. Any of these physical findings may warrant further evaluation, and thus leads to an incidental diagnosis of multiple myeloma. | ||
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Revision as of 15:32, 21 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with multiple usually appear fatigued and lethargic.[1][2] Physical examination of patients with multiple myeloma is usually remarkable for pallor, purpura, hepatosplenomegaly, carpal tunnel syndrome, and signs of cord compression.[3][4] Multiple myeloma affects not only the bone marrow, but also spreads to other organ systems. This therefore, requires a detailed assessment of various organ systems. Any of these physical findings may warrant further evaluation, and thus leads to an incidental diagnosis of multiple myeloma.
Physical Examination
General appearance
- Lethargic
- Fatigued
Vital Signs
- Low-grade fever
HEENT
- Lymphadenopathy
- Conjuctival pallor
- Visual defects
- Exudative macular detachment
- Retinal haemorrhage
- Increased fat around the neck
- Cotton-wool spots
- Shoulder pad sign - amyloid deposition around shoulders.
Cardiovascular
- Cardiomyopathy
Abdomen
Skeletal
Skin
CNS
- Altered sensation
- Dermatomal sensory loss
- Polyeuropathy
References
- ↑ Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma#Signs_and_symptoms Accessed on September, 20th 2015
- ↑ Multiple myeloma. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/signs-and-symptoms/?region=mb Accessed on September 20th 2015
- ↑ Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma#Signs_and_symptoms Accessed on September, 20th 2015
- ↑ Multiple myeloma. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/signs-and-symptoms/?region=mb Accessed on September 20th 2015