DRESS syndrome epidemiology and demographics: Difference between revisions
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{{DRESS syndrome}} | {{DRESS syndrome}} | ||
{{CMG}}; {{AE}} {{YD}}; {{SSK}} | {{CMG}}; {{AE}} {{YD}}; {{SSK}} | ||
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==Overview== | ==Overview== | ||
The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures. The case-fatality rate of DRESS syndrome is approximately 10%. DRESS syndrome has been reported among patients of all ages with no gender or racial predilection. | The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures. The case-fatality rate of DRESS syndrome is approximately 10%. DRESS syndrome has been reported among patients of all ages with no gender or racial predilection. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
*The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures.<ref name="pmid14632808">{{cite journal| author=Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B et al.| title=A 6-month prospective survey of cutaneous drug reactions in a hospital setting. | journal=Br J Dermatol | year= 2003 | volume= 149 | issue= 5 | pages= 1018-22 | pmid=14632808 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14632808 }} </ref> | *The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures.<ref name="pmid14632808">{{cite journal| author=Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B et al.| title=A 6-month prospective survey of cutaneous drug reactions in a hospital setting. | journal=Br J Dermatol | year= 2003 | volume= 149 | issue= 5 | pages= 1018-22 | pmid=14632808 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14632808 }} </ref> | ||
===Case-Fatality Rate=== | ===Case-Fatality Rate=== | ||
*The case-fatality rate of DRESS syndrome is approximately 10%. | *The case-fatality rate of DRESS syndrome is approximately 10%. | ||
===Age=== | ===Age=== | ||
*DRESS syndrome affects patients of all ages and has been reported among pediatric, adult, and elderly patients.<ref name="pmid14632808">{{cite journal| author=Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B et al.| title=A 6-month prospective survey of cutaneous drug reactions in a hospital setting. | journal=Br J Dermatol | year= 2003 | volume= 149 | issue= 5 | pages= 1018-22 | pmid=14632808 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14632808 }} </ref> | *DRESS syndrome affects patients of all ages and has been reported among pediatric, adult, and elderly patients.<ref name="pmid14632808">{{cite journal| author=Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B et al.| title=A 6-month prospective survey of cutaneous drug reactions in a hospital setting. | journal=Br J Dermatol | year= 2003 | volume= 149 | issue= 5 | pages= 1018-22 | pmid=14632808 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14632808 }} </ref> | ||
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:*The median age for the development of DRESS syndrome is approximately 40-50 years among adult patients.<ref name="pmid21592453">{{cite journal| author=Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L et al.| title=The DRESS syndrome: a literature review. | journal=Am J Med | year= 2011 | volume= 124 | issue= 7 | pages= 588-97 | pmid=21592453 | doi=10.1016/j.amjmed.2011.01.017 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21592453 }} </ref><ref name="pmid20713773">{{cite journal| author=Chen YC, Chiu HC, Chu CY| title=Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases. | journal=Arch Dermatol | year= 2010 | volume= 146 | issue= 12 | pages= 1373-9 | pmid=20713773 | doi=10.1001/archdermatol.2010.198 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20713773 }} </ref> | :*The median age for the development of DRESS syndrome is approximately 40-50 years among adult patients.<ref name="pmid21592453">{{cite journal| author=Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L et al.| title=The DRESS syndrome: a literature review. | journal=Am J Med | year= 2011 | volume= 124 | issue= 7 | pages= 588-97 | pmid=21592453 | doi=10.1016/j.amjmed.2011.01.017 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21592453 }} </ref><ref name="pmid20713773">{{cite journal| author=Chen YC, Chiu HC, Chu CY| title=Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases. | journal=Arch Dermatol | year= 2010 | volume= 146 | issue= 12 | pages= 1373-9 | pmid=20713773 | doi=10.1001/archdermatol.2010.198 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20713773 }} </ref> | ||
:*The median age for the development of DRESS syndrome is approximately 10-12 years among pediatric patients.<ref name="pmid11483822">{{cite journal| author=Carroll MC, Yueng-Yue KA, Esterly NB, Drolet BA| title=Drug-induced hypersensitivity syndrome in pediatric patients. | journal=Pediatrics | year= 2001 | volume= 108 | issue= 2 | pages= 485-92 | pmid=11483822 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11483822 }} </ref> | :*The median age for the development of DRESS syndrome is approximately 10-12 years among pediatric patients.<ref name="pmid11483822">{{cite journal| author=Carroll MC, Yueng-Yue KA, Esterly NB, Drolet BA| title=Drug-induced hypersensitivity syndrome in pediatric patients. | journal=Pediatrics | year= 2001 | volume= 108 | issue= 2 | pages= 485-92 | pmid=11483822 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11483822 }} </ref> | ||
===Gender=== | ===Gender=== | ||
*There is no gender predilection to the development of DRESS syndrome. | *There is no gender predilection to the development of DRESS syndrome. | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Hepatology]] | [[Category:Hepatology]] | ||
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{{WH}} | |||
Revision as of 12:17, 20 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.
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Overview
The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures. The case-fatality rate of DRESS syndrome is approximately 10%. DRESS syndrome has been reported among patients of all ages with no gender or racial predilection.
Epidemiology and Demographics
Incidence
- The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures.[1]
Case-Fatality Rate
- The case-fatality rate of DRESS syndrome is approximately 10%.
Age
- DRESS syndrome affects patients of all ages and has been reported among pediatric, adult, and elderly patients.[1]
- In modest-sized observational studies and case series:
Gender
- There is no gender predilection to the development of DRESS syndrome.
Race
- There is no racial predilection to the development of DRESS syndrome.
References
- ↑ 1.0 1.1 Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B; et al. (2003). "A 6-month prospective survey of cutaneous drug reactions in a hospital setting". Br J Dermatol. 149 (5): 1018–22. PMID 14632808.
- ↑ Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L; et al. (2011). "The DRESS syndrome: a literature review". Am J Med. 124 (7): 588–97. doi:10.1016/j.amjmed.2011.01.017. PMID 21592453.
- ↑ Chen YC, Chiu HC, Chu CY (2010). "Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases". Arch Dermatol. 146 (12): 1373–9. doi:10.1001/archdermatol.2010.198. PMID 20713773.
- ↑ Carroll MC, Yueng-Yue KA, Esterly NB, Drolet BA (2001). "Drug-induced hypersensitivity syndrome in pediatric patients". Pediatrics. 108 (2): 485–92. PMID 11483822.